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Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices

Title
Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices
Author(s)
Kim, Jae YoungSeo, Eun SeokLim, Hee JinKim, Hyun MinPark, J.-W.Shin, H.H.Lim, D.-K.Moon, Dae Won
DGIST Authors
Kim, Jae YoungSeo, Eun SeokLim, Hee JinKim, Hyun MinPark, J.-W.Shin, H.H.Lim, D.-K.Moon, Dae Won
Issued Date
2018-02
Type
Article
Article Type
Article
Keywords
ELECTROSPRAY-IONIZATIONFIBER LASERMOLECULESGRAPHENEMATRIXMEMORYMS
ISSN
2046-2069
Abstract
Micrometer-resolution mass spectrometric imaging of live hippocampal tissue is achieved with a highly efficient desorption of biomolecules using a 532 nm continuous wave laser and gold nanoparticles or graphene oxide as an energy transporter, which enables clear identification of the distributions of monoacylglycerol, adenine, cholesterol, sphingosine and ceramide. © The Royal Society of Chemistry 2018.
URI
http://hdl.handle.net/20.500.11750/6164

http://pubs.rsc.org/en/content/articlelanding/2018/ra/c8ra00038g#!divAbstract
DOI
10.1039/c8ra00038g
Publisher
Royal Society of Chemistry

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