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Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices
- Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices
- Kim, Jae Young; Seo, Eun Seok; Lim, Hee Jin; Kim, Hyun Min; Park, J.-W.; Shin, H.H.; Lim, D.-K.; Moon, Dae Won
- DGIST Authors
- Kim, Jae Young; Kim, Hyun Min; Moon, Dae Won
- Issue Date
- RSC Advances, 8(15), 8021-8025
- Article Type
- Atmospheric pressure; Continuous wave lasers; Desorption; Gold compounds; Gold nanoparticles; Graphene; Graphene oxide; Mass spectrometers; Mass spectrometry; Tissue; Mass spectrometric imaging; Monoacylglycerol; Sphingosine; Tissue slice; Spectrometry
- Micrometer-resolution mass spectrometric imaging of live hippocampal tissue is achieved with a highly efficient desorption of biomolecules using a 532 nm continuous wave laser and gold nanoparticles or graphene oxide as an energy transporter, which enables clear identification of the distributions of monoacylglycerol, adenine, cholesterol, sphingosine and ceramide. © The Royal Society of Chemistry 2018.
- Royal Society of Chemistry
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- Companion Diagnostics and Medical Technology Research Group1. Journal Articles
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