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Detection of Protein Molecules by Electrical Current Response Using Two-Electrode Method

Title
Detection of Protein Molecules by Electrical Current Response Using Two-Electrode Method
Authors
Lyu, Hong KunWoo, Sung HoHan, Yoon SooLee, Hee-HoShin, Jang-Kyoo
DGIST Authors
Lyu, Hong KunWoo, Sung Ho; Han, Yoon Soo; Lee, Hee-Ho; Shin, Jang-Kyoo
Issue Date
2011
Citation
Journal of Sensor Science and Technology, 20(2), 90-95
Type
Article
ISSN
2093-7563
Abstract
In order to protect human lives from disease, various biosensors having the potential to analyze a variety of biomolecules have been utilized. Biosensors constitute one of the most promising ways to monitor and detect various biomolecules corresponding to diseases. In this study, we demonstrate that the reaction of streptavidin molecules with biotin on a gold electrode can be detected using the twoelectrode method with a gold electrode and a platinum reference electrode. We also show the characteristics of the electrical current response. While detecting 2- streptavidin molecules dissolved in phosphate buffered saline(PBS) solution, we found that an analytical biosensor can operate on the principle of detecting an antigen-antibody reaction event of protein molecules using the two-electrode method. We think that the "potential step" method might be useful to detect the occurrence of any antigen-antibody reactions and can be combined with other devices or ICs such as BJTs, MOSFETs, and OP-amps for the detection of biomolecules of diseases
URI
http://hdl.handle.net/20.500.11750/6496
DOI
10.5369/JSST.2011.20.2.90
Publisher
The Korean Sensors Society
Related Researcher
Files:
There are no files associated with this item.
Collection:
Division of Electronics & Information System1. Journal Articles
Division of Energy Technology1. Journal Articles
ETC1. Journal Articles


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