Cited 5 time in webofscience Cited 4 time in scopus

Molecular Mechanisms of Synaptic Specificity: Spotlight on Hippocampal and Cerebellar Synapse Organizers

Title
Molecular Mechanisms of Synaptic Specificity: Spotlight on Hippocampal and Cerebellar Synapse Organizers
Authors
Park, DongseokBae, SungwonYoon, Taek HanKo, Jaewon
DGIST Authors
Park, Dongseok; Bae, Sungwon; Yoon, Taek Han; Ko, Jaewon
Issue Date
2018-05
Citation
Molecules and Cells, 41(5), 373-380
Type
Article
Article Type
Review
Author Keywords
brain disorderneural circuitspecificitysynapsesynaptic adhesion
Keywords
PARALLEL FIBER SYNAPSESFAMILY MESSENGER-RNASPURKINJE-CELL SYNAPSEENTORHINAL CORTEXNEURAL CIRCUITSCLIMBING FIBERTRANSSYNAPTIC INTERACTIONPRESYNAPTIC NEUREXIN-3EXCITATORY SYNAPSESDISTINCT EXPRESSION
ISSN
1016-8478
Abstract
Synapses and neural circuits form with exquisite specificity during brain development to allow the precise and appropriate flow of neural information. Although this property of synapses and neural circuits has been extensively investigated for more than a century, molecular mechanisms underlying this property are only recently being unveiled. Recent studies highlight several classes of cell-surface proteins as organizing hubs in building structural and functional architectures of specific synapses and neural circuits. In the present minireview, we discuss recent findings on various synapse organizers that confer the distinct properties of specific synapse types and neural circuit architectures in mammalian brains, with a particular focus on the hippocampus and cerebellum.
URI
http://hdl.handle.net/20.500.11750/6647
DOI
10.14348/molcells.2018.0081
Publisher
한국분자세포생물학회
Related Researcher
  • Author Ko, Jaewon Laboratory of Synapse Formation and Function
  • Research Interests Synapse Formation and Function; Neural Circuits; 뇌질환; animal model
Files:
There are no files associated with this item.
Collection:
Department of Brain and Cognitive SciencesLaboratory of Synapse Formation and Function1. Journal Articles


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