DGIST Scholar: 이병훈

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researcher image '이병훈'

이병훈 (Lee, Byung-Hoon)

ISNI Researcher ID ORCiD Scopus Google Scholar Research Gate

Department: Department of New Biology

Affiliated Community: Lab of Protein Homeostasis and Drug Discovery

Research Interests: Ubiquitin-proteasome system; Protein homeostasis; Small-molecule chemical screening and drug discovery in human disease

Website: https://proteolysis.dgist.ac.kr/main/main.php

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Issue Date	Title Author(s) Journal	View
2024-12	Pharmacological inhibition of USP14 delays proteostasis-associated aging in a proteasome-dependent but foxo-independent manner Lim, Jin Ju ; Noh, Sujin ; Kang, Woojun ; Hyun, Bom ; Lee, Byung-Hoon ; Hyun, Seogang Autophagy, v.20, no.12, pp.2752 - 2768, 2024-12	39
2024-06	Biallelic USP14 variants cause a syndromic neurodevelopmental disorder Ebstein, Frédéric ; Latypova, Xenia ; Sharon Hung, Ka Ying ; Prado, Miguel A. ; Lee, Byung-Hoon ; Möller, Sophie ; Wendlandt, Martin ; Zieba, Barbara A. ; Florenceau, Laëtitia ; Vignard, Virginie ; et al Genetics in Medicine, v.26, no.6, 2024-06	129
2024-06	Structural Dynamics Analysis of USP14 Activation by AKT-Mediated Phosphorylation Dash, Raju ; Tran, Non-Nuoc ; Lee, Sung Bae ; Lee, Byung-Hoon Cells, v.13, no.11, 2024-06	137
2023-01	Orally bioavailable BTK PROTAC active against wild-type and C481 mutant BTKs in human lymphoma CDX mouse models Lim, Ye Seul ; Yoo, Sun-Mi ; Patil, Vineet ; Kim, Han Wool ; Kim, Hyun-Hwi ; Suh, Beomseon ; Park, Ji Youn ; Jeong, Na-rae ; Park, Chi Hoon ; Ryu, Je Ho ; et al Blood Advances, v.7, no.1, pp.92 - 105, 2023-01	276
2022-11	Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1 Chung, Scisung ; Kang, Mi-Sun ; Alimbetov, Dauren S. ; Mun, Gil-Im ; Yunn, Na-Oh ; Kim, Yunjin ; Kim, Byung-Gyu ; Wie, Minwoo ; Lee, Eun A. ; Ra, Jae Sun ; et al Nature Communications, v.13, no.1, 2022-11	233
2022-09	Functional implication of ubiquitinating and deubiquitinating mechanisms in TDP-43 proteinopathies Tran, Non-Nuoc ; Lee, Byung-Hoon Frontiers in Cell and Developmental Biology, v.10, 2022-09	277
2022-02	Allosteric control of Ubp6 and the proteasome via a bidirectional switch Hung, Ka Ying Sharon ; Klumpe, Sven ; Eisele, Markus R. ; Elsasser, Suzanne ; Tian, Geng ; Sun, Shuangwu ; Moroco, Jamie A. ; Cheng, Tat Cheung ; Joshi, Tapan ; Seibel, Timo ; et al Nature Publishing Group, 2022-02	352
2021-06	Small-molecule inhibitors targeting proteasome-associated deubiquitinases Moon, Seonghyeon ; Muniyappan, Srinivasan ; Lee, Sung Bae ; Lee, Byung-Hoon Multidisciplinary Digital Publishing Institute (MDPI), 2021-06	443
2021-03	GSK3B induces autophagy by phosphorylating ULK1 Ryu, Hye Young ; Kim, Eunjung Leah ; Jeong, Hyeonjeong ; Yeo, Bo Kyoung ; Lee, Ji Won ; Nam, Hyeri ; Ha, Shinwon ; An, Hyun-Kyu ; Park, Hyunhee ; Jung, Seonghee ; et al Experimental and Molecular Medicine, v.53, no.3, pp.369 - 383, 2021-03	496
2020-10	Ataxin-2 Dysregulation Triggers a Compensatory Fragile X Mental Retardation Protein Decrease in Drosophila C4da Neurons Cha, InJun ; Lee, Davin ; Park, Sung Soon ; Chung, Chang Geon ; Kim, Seung Yeon ; Jo, Min Gu ; Kim, SeungYeol ; Lee, Byung-Hoon ; Lee, Young-Sam ; Lee, Sung Bae Korean Society for Molecular and Cellular Biology, 2020-10	526
2020-09	C9orf72-Associated Arginine-Rich Dipeptide Repeat Proteins Reduce the Number of Golgi Outposts and Dendritic Branches in Drosophila Neurons Park, Jeong Hyang ; Chung, Chang Geon ; Seo, Jinsoo ; Lee, Byung-Hoon ; Lee, Young-Sam ; Kweon, Jung Hyun ; Lee, Sung Bae 한국분자세포생물학회, 2020-09	505
2020-08	Deubiquitination Reactions on the Proteasome for Proteasome Versatility Shin, Ji Yeong ; Muniyappan, Srinivasan ; Tran, Non-Nuoc ; Park, Hyeonjeong ; Lee, Sung Bae ; Lee, Byung-Hoon International Journal of Molecular Sciences, v.21, no.15, pp.5312 - 16, 2020-08	662
2019-12	Proteasome subunit RPT2a promotes PTGS through repressing RNA quality control in Arabidopsis Kim, Myung-Hee ; Jeon, Ji. eun. ; Lee, Seulbee ; Lee, Jae. Ho. ; Gao, Lei ; Lee, Byung-Hoon ; Park, Jeong Mee ; Kim, Yun Ju ; Kwak, June Myoung Palgrave Macmillan Ltd., 2019-12	881
2019-03	The deubiquitinating enzyme USP14 controls ciliogenesis and hedgehog signalling Massa, Filomena ; Tammaro, Roberta ; Prado, Miguel A ; Cesana, Marcella ; Lee, Byung Hoon ; Finley, Daniel ; Franco, Brunella ; Morleo, Manuela Oxford University Press, 2019-03	619
2019-02	In vitro analysis of proteasome-associated USP14 activity for substrate degradation and deubiquitylation Muniyappan, Srinivasan ; Lee, Byung-Hoon Methods in Enzymology, v.619, pp.249 - 268, 2019-02	697
2018-11	Chemically Induced Cellular Proteolysis: An Emerging Therapeutic Strategy for Undruggable Targets Moon, Seonghyeon ; Lee, Byung Hoon Molecules and Cells, v.41, no.11, pp.933 - 942, 2018-11	695
2017-11	An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons Boselli, Monica ; Lee, Byung Hoon ; Robert, Jessica ; Prado, Miguel A. ; Min, Sang-Won ; Cheng, Chialin ; Silva, M. Catarina ; Seong, Changhyun ; Elsasser, Suzanne ; Hatle, Ketki M. ; et al AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2017-11	725

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