김유리
Kim, Yoori학력
- 2013 ~ 2018University of Texas at Austin 박사
- 2009 ~ 2011서강대학교 석사
- 2004 ~ 2009서강대학교 학사
경력
- 2019 ~ 2021UT Southwestern Medical Center / Postdoctoral Researcher
수상실적
연구실 소개
- Molecular Epigenetics Lab
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Our cells can pack nearly ~2 meters of DNA into a ~10μm nucleus, while still being able to accurately read, replicate, and segregate this tightly condensed genome. Each of us has enough DNA to reach from here to the sun and back, more than 300 times.How is that entire genomic DNA organized in a tiny nucleus? How does the nucleus maintain this vast amount of information throughout life and how is it connected to human aging and diseases?We aim to decipher the molecular mechanisms that allow cells to organize and maintain their genome throughout life. We pursue to deepen our understanding by using approaches that integrate single-molecule biophysics, cell imaging and computational analysis, nano/micro engineering, and molecular biology.
Research Interests
Related Keyword
- "CTCF and R-loops are boundaries of cohesin-mediated DNA looping", Zhang, Hongshan. (2023-08). CTCF and R-loops are boundaries of cohesin-mediated DNA looping. Molecular Cell, 83(16), 2856-2871.e8. doi: 10.1016/j.molcel.2023.07.006
- "Regulation of loop extrusion on the interphase genome", Shin, Hyogyung. (2023-01). Regulation of loop extrusion on the interphase genome. Critical Reviews in Biochemistry and Molecular Biology, 58(1), 1–18. doi: 10.1080/10409238.2023.2182273
- "Fluid-driven DNA stretching for single-molecule studies on chromatin-associated proteins", Heo, Wonje. (2022-12). Fluid-driven DNA stretching for single-molecule studies on chromatin-associated proteins. Biochemical and Biophysical Research Communications, 634, 122–128. doi: 10.1016/j.bbrc.2022.10.023
연구 뉴스
- 유전체의 3차원 구조를 밝힌다 2022-12-30