Our group focuses on the chemical biology of protein post-translational modifications (PTMs) and thier molecular interactions that are relevant in brain and neurological disorders. We integrate chemical, biochemical, structural, and biological approaches such as peptide synthesis, protein engineering, biochemical assays, and cellular experiments to elucidate the functions of chemically modified proteins in vitro and in living cells. Our long-term objective is to identify the specific protein PTMs that drive the progression of brain and neurological diseases and to unravel their underlying molecular mechanisms.
We are looking for undergraduate and graduate students who are interested in biochemistry, protein chemistry, chemical biology, and neurochemistry. Highly motivated individuals with strong curiosity and an interest in protein modifications, protein engineering, biochemical interactions, and interdisciplinary approaches bridging chemistry and biology are encouraged to apply.Please contact the PI via email with a brief description of your research interests (for UGRP, undergraduate internships, and graduate student positions).