DGIST Scholar: 이영삼

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이영삼(Lee, Young-Sam)

ISNI Researcher ID ORCiD Scopus Google Scholar Research Gate

Department: Department of New Biology

Affiliated Community: Senescence-Associated Mechanism Lab

Research Interests: DNA replication and repair; Restoration of cellular senescence; Structural and functional relationship of proteins

Website: https://newbiology.dgist.ac.kr/professor/yslee

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Issue Date	Title Author(s) Journal	View
2022-09	Nintedanib induces senolytic effect via STAT3 inhibition Cho, Hyun-Ji ; Hwang, Jeong-A ; Yang, Eun Jae ; Kim, Eok-Cheon ; Kim, Jae-Ryong ; Kim, Sung Young ; Kim, Young Zoon ; Park, Sang Chul ; Lee, Young-Sam Nature Publishing Group, 2022-09	56
2022-07	Co-inhibition of ATM and ROCK synergistically improves cell proliferation in replicative senescence by activating FOXM1 and E2F1 Yang, Eun Jae ; Park, Ji Hwan ; Cho, Hyun-Ji ; Hwang, Jeong-A ; Woo, Seung Hwa ; Park, Chi Hyun ; Kim, Sung Young ; Park, Joon Tae ; Park, Sang Chul ; Hwang, Daehee ; et al Nature Publishing Group, 2022-07	58
2022-07	Hypo-trimethylation of Histone H3 Lysine 4 and Hyper-tri/dimethylation of Histone H3 Lysine 27 as Epigenetic Markers of Poor Prognosis in Patients with Primary Central Nervous System Lymphoma Kim, Hoon Gi ; Kim, Minseok S. ; Lee, Young-Sam ; Lee, Eun Hee ; Kim, Dae Cheol ; Lee, Sung-Hun ; Kim, Young Zoon 대한암학회, 2022-07	187
2021-10	Neuromyelitis optica (NMO)‐IgG‐driven organelle reorganization in human iPSC‐derived astrocytes Cho, Sukhee ; Lee, Hyein ; Jung, Minkyo ; Hong, Kirim ; Woo, Seung Hwa ; Lee, Young-Sam ; Kim, Byoung Joon ; Jeon, Mi Young ; Seo, Jinsoo ; Mun, Ji Young Federation of American Societies for Experimental Biology, 2021-10	251
2021-06	Disruption of nucleocytoplasmic trafficking as a cellular senescence driver Park, Ji-Hwan ; Ryu, Sung Jin ; Kim, Byung Ju ; Cho, Hyun-Ji ; Park, Chi Hyun ; Choi, Hyo Jei Claudia ; Jang, Eun Jin ; Yang, Eun Jae ; Hwang, Jeong-A ; Woo, Seung Hwa ; et al Springer Nature, 2021-06	256
2020-11	ATM mediated-p53 signaling pathway forms a novel axis for senescence control Hwang, Su Young ; Kuk, Myeong Uk ; Kim, Jae Won ; Lee, Yun Haeng ; Lee, Young-Sam ; Choy, Hyon E ; Park, Sang Chul ; Park, Joon Tae Elsevier B.V., 2020-11	304
2020-10	Ataxin-2 Dysregulation Triggers a Compensatory Fragile X Mental Retardation Protein Decrease in Drosophila C4da Neurons Cha, InJun ; Lee, Davin ; Park, Sung Soon ; Chung, Chang Geon ; Kim, Seung Yeon ; Jo, Min Gu ; Kim, SeungYeol ; Lee, Byung-Hoon ; Lee, Young-Sam ; Lee, Sung Bae Korean Society for Molecular and Cellular Biology, 2020-10	343
2020-09	C9orf72-Associated Arginine-Rich Dipeptide Repeat Proteins Reduce the Number of Golgi Outposts and Dendritic Branches in Drosophila Neurons Park, Jeong Hyang ; Chung, Chang Geon ; Seo, Jinsoo ; Lee, Byung-Hoon ; Lee, Young-Sam ; Kweon, Jung Hyun ; Lee, Sung Bae 한국분자세포생물학회, 2020-09	303
2020-08	Satellite cell-specific ablation of Cdon impairs integrin activation, FGF signalling, and muscle regeneration Bae, Ju-Hyeon ; Hong, Mingi ; Jeong, Hyeon-Ju ; Kim, Hyebeen ; Lee, Sang-Jin ; Ryu, Dongryeol ; Bae, Gyu-Un ; Cho, Sung Chun ; Lee, Young-Sam ; Krauss, Robert S. ; et al Wiley, 2020-08	472
2020-08	Global transcriptional downregulation of TREX and nuclear trafficking machinery as pan-senescence phenomena: evidence from human cells and tissues Kim, Sung Young ; Yang, Eun Jae ; Lee, Sung Bae ; Lee, Young-Sam ; Cho, Kyoung A. ; Park, Sang Chul Springer Nature, 2020-08	427
2020-06	The Mechanisms of Nuclear Proteotoxicity in Polyglutamine Spinocerebellar Ataxias Lee, Davin ; Lee, Yun-Il ; Lee, Young-Sam ; Lee, Sung-Bae Frontiers Media S.A., 2020-06	181
2020-05	Identification of SYK inhibitor, R406 as a novel senolytic agent Cho, Hyun-Ji ; Yang, Eun Jae ; Park, Joon Tae ; Kim, Jae-Ryong ; Kim, Eok-Cheon ; Jung, Kyong-Jin ; Park, Sang Chul ; Lee, Young-Sam Impact Journals, 2020-05	459
2019-03	Alleviation of Senescence via ATM Inhibition in Accelerated Aging Models Kuk, Myeong Uk ; Kim, Jae Won ; Lee, Young-Sam ; Cho, Kyung A. ; Park, Joon Tae ; Park, Sang Chul 한국분자세포생물학회, 2019-03	475
2019	Quantification of Autophagy During Senescence Park, Joon Tae ; Lee, Young-Sam ; Park, Sang Chul Humana Press Inc., 2019	494
2018-11	Adjustment of the lysosomal-mitochondrial axis for control of cellular senescence Park, Joon Tae ; Lee, Young-Sam ; Cho, Kyung A. ; Park, Sang Chul Elsevier Ireland Ltd, 2018-11	569
2018-06	A crucial role of ROCK for alleviation of senescence-associated phenotype Park, J.T. ; Kang, H.T. ; Park, C.H. ; Lee, Young Sam ; Cho, K.A. ; Park, Sang Chul Elsevier BV, 2018-06	628
2017-06	Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson-Gilford progeria syndrome Kang, Hyun Tae ; Park, Joon Tae ; Choi, Kobong ; Choi, Hyo Jei Claudia ; Jung, Chul Won ; Kim, Gyu Ree ; Lee, Young-Sam ; Park, Sang Chul WILEY, 2017-06	706
2017-06	Chemical screening identifies ATM as a target for alleviating senescence Kang, Hyun Tae ; Park, Joon Tae ; Choi, Kobong ; Kim, Yongsub ; Choi, Hyo Jei Claudia ; Jung, Chul Won ; Lee, Young-Sam ; Park, Sang Chul NATURE PUBLISHING GROUP, 2017-06	869
2017-03	Systematic identification of an integrative network module during senescence from time-series gene expression Park, Chihyun ; Yun, So Jeong ; Ryu, Sung Jin ; Lee, Soyoung ; Lee, Young-Sam ; Yoon, Youngmi ; Park, Sang Chul BIOMED CENTRAL LTD, 2017-03	692
2016-10	Six Germline Genetic Variations Impair the Translesion Synthesis Activity of Human DNA Polymerase kappa Kim, JK[Kim, Jae-Kwon] ; Yeom, M[Yeom, Mina] ; Hong, JK[Hong, Jin-Kyung] ; Song, I[Song, Insil] ; Lee, YS[Lee, Young-Sam] ; Guengerich, FP[Guengerich, F. Peter] ; Choi, JY[Choi, Jeong-Yun] American Chemical Society, 2016-10	623