Senescence-Associated Mechanism Lab42
Research Summary
Our objective is to restore cellular function in senescent stage by genome maintenance-based approach
To pursue the objective, we carry out the following research topics:
1. Identify small molecules/genetic factors inducing physiological restoration of senescent cells and DNA repair capability. Figure out the mechanism of action in the restoration by the selected factors.
2. Interpret the structure based function in DNA replication utilizing physiologically relevant damaged DNA substrates.
3. Investigate the role of RNA transcripts (e.g. long noncoding RNAs) and their binding factors in DNA repair regarding cellular senescence.
Advisor Professor : Lee, Young-Sam
Senescence-Associated Mechanism Lab Homepage
Our objective is to restore cellular function in senescent stage by genome maintenance-based approach
To pursue the objective, we carry out the following research topics:
1. Identify small molecules/genetic factors inducing physiological restoration of senescent cells and DNA repair capability. Figure out the mechanism of action in the restoration by the selected factors.
2. Interpret the structure based function in DNA replication utilizing physiologically relevant damaged DNA substrates.
3. Investigate the role of RNA transcripts (e.g. long noncoding RNAs) and their binding factors in DNA repair regarding cellular senescence.
Advisor Professor : Lee, Young-Sam
Senescence-Associated Mechanism Lab Homepage
- Subject
- 5 CELLULAR SENESCENCE
- 4 Autophagy
- 4 DNA-DAMAGE
- 4 EXPRESSION
- 4 LIFE-SPAN
- 4 Senescence
- 3 Aging
- 3 APOPTOSIS
- 3 CANCER
- 3 CELLS
Co-Author(s)
Related Keyword
Recent Submissions
RSS 1.0
RSS 2.0
ATOM 1.0
- Brief guide to senescence assays using cultured mammalian cells
- The ICL1 and MLS1 Genes, Integral to the Glyoxylate Cycle, are Essential and Specific for Caloric Restriction-Mediated Extension of Lifespan in Budding Yeast
- Animal-free scaffold from brown algae provides a three-dimensional cell growth and differentiation environment for steak-like cultivated meat
- 세노모르픽(senomorphics)용 병용 조성물
- From Homogeneity to Turing Pattern: Kinetically Controlled Self-Organization of Transmembrane Protein