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Showing results 1 to 8 of 8

Article
ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells
  • Lee, Jiyeon ; 
  • Lee, Haeryung ; 
  • Lee, Hyein ; 
  • Shin, Miram ; 
  • Shin, Min-Gi ; 
  • Seo, Jinsoo ; 
  • Lee, Eun Jeong ; 
  • Park, Sun Ah ; 
  • Park, Soochul
  • 2023-12
  • Lee, Jiyeon. (2023-12). ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells. Nature Communications, 14(1). doi: 10.1038/s41467-023-44319-3
  • Nature Publishing Group
  • View : 232
  • Download : 38

APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation

Article
APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation
  • Lee, Se-In ; 
  • Jeong, Woojin ; 
  • Lim, Heejin ; 
  • Cho, Sukhee ; 
  • Lee, Hyein ; 
  • Jang, Yonghee ; 
  • Cho, Joonho ; 
  • Bae, Simsung ; 
  • Lin, Yuan-Ta ; 
  • Tsai, Li-Huei ; 
    • et al
  • 2021-09
  • Lee, Se-In. (2021-09). APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation. Stem Cell Reports, 16(9), 2128–2137. doi: 10.1016/j.stemcr.2021.07.017
  • Cell Press
  • View : 832
  • Download : 65

ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes

Article
ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes
  • Lee, Hyein ; 
  • Cho, Sukhee ; 
  • Kim, Mi-Jin ; 
  • Park, Yeo Jin ; 
  • Cho, Eunji ; 
  • Jo, Yeon Suk ; 
  • Kim, Yong-Seok ; 
  • Lee, Jung Yi ; 
  • Thoudam, Themis ; 
  • Woo, Seung-Hwa ; 
    • et al
  • 2023-10
  • Lee, Hyein. (2023-10). ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes. Cell Reports, 42(10). doi: 10.1016/j.celrep.2023.113183
  • Cell Press
  • View : 366
  • Download : 61
Article
ApoE4-Induced Cholesterol Dysregulation and Its Brain Cell Type-Specific Implications in the Pathogenesis of Alzheimer's Disease
  • Jeong, Woojin ; 
  • Lee, Hyein ; 
  • Cho, Sukhee ; 
  • Seo, Jinsoo
  • 2019-11
  • Jeong, Woojin. (2019-11). ApoE4-Induced Cholesterol Dysregulation and Its Brain Cell Type-Specific Implications in the Pathogenesis of Alzheimer's Disease. Molecules and Cells, 42(11), 739–746. doi: 10.14348/molcells.2019.0200
  • 한국분자세포생물학회
  • View : 766
  • Download : 0

Astrocyte priming enhances microglial Aβ clearance and is compromised by APOE4

Article
Astrocyte priming enhances microglial Aβ clearance and is compromised by APOE4
  • Lee, Se-In ; 
  • Yu, Jichang ; 
  • Lee, Hyein ; 
  • Kim, Buyun ; 
  • Jang, Min Jun ; 
  • Jo, Hyeonbin ; 
  • Kim, Na Yeon ; 
  • Pak, Malk Eun ; 
  • Kim, Jae Kwang ; 
  • Cho, Sukhee ; 
    • et al
  • 2025-08
  • Nature Communications, v.16, no.1
  • Nature Publishing Group
  • View : 66
  • Download : 14

Imaging lipid rafts reveals the principle of ApoE4-induced AR upregulation in human neurons

Article
Imaging lipid rafts reveals the principle of ApoE4-induced AR upregulation in human neurons
  • Lee, Se-In ; 
  • Lim, Heejin ; 
  • Kim, Na Yeon ; 
  • Yu, Jichang ; 
  • Cho, Joonho ; 
  • Lee, Hyein ; 
  • Moon, Dae Won ; 
  • Seo, Jinsoo
  • 2025-02
  • Lee, Se-In. (2025-02). Imaging lipid rafts reveals the principle of ApoE4-induced AR upregulation in human neurons. iScience, 28(2). doi: 10.1016/j.isci.2025.111893
  • Cell Press
  • View : 128
  • Download : 71
Article
Impact of Genetic Risk Factors for Alzheimer’s Disease on Brain Glucose Metabolism
  • 2021-06
  • Cho, Sukhee. (2021-06). Impact of Genetic Risk Factors for Alzheimer’s Disease on Brain Glucose Metabolism. Molecular Neurobiology, 58(6), 2608–2619. doi: 10.1007/s12035-021-02297-x
  • Springer
  • View : 623
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Article
Neuromyelitis optica (NMO)‐IgG‐driven organelle reorganization in human iPSC‐derived astrocytes
  • Cho, Sukhee ; 
  • Lee, Hyein ; 
  • Jung, Minkyo ; 
  • Hong, Kirim ; 
  • Woo, Seung Hwa ; 
  • Lee, Young-Sam ; 
  • Kim, Byoung Joon ; 
  • Jeon, Mi Young ; 
  • Seo, Jinsoo ; 
  • Mun, Ji Young
  • 2021-10
  • Cho, Sukhee. (2021-10). Neuromyelitis optica (NMO)‐IgG‐driven organelle reorganization in human iPSC‐derived astrocytes. doi: 10.1096/fj.202100637r
  • Federation of American Societies for Experimental Biology
  • View : 641
  • Download : 0
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