Cited time in webofscience Cited time in scopus

Full metadata record

DC Field Value Language Park, Hyungju ko Kaang, Bong-Kiun ko 2019-10-16T12:57:01Z - 2019-10-16T12:57:01Z - 2019-09-22 - 2019-09 -
dc.identifier.citation Learning and Memory, v.26, no.9, pp.299 - 306 -
dc.identifier.issn 1072-0502 -
dc.identifier.uri -
dc.description.abstract Storage of long-term memory requires not only protein synthesis but also protein degradation. In this article, we overview recent publications related to this issue, stressing that the balanced actions of protein synthesis and degradation are critical for long-term memory formation. We particularly focused on the brain-derived neurotrophic factor signaling that leads to protein synthesis; proteasome- and autophagy-dependent protein degradation that removes molecular constraints; the role of Fragile X mental retardation protein in translational suppression; and epigenetic modifications that control gene expression at the genomic level. Numerous studies suggest that an imbalance between protein synthesis and degradation leads to intellectual impairment and cognitive disorders. © 2019 Park and Kaang; Published by Cold Spring Harbor Laboratory Press. -
dc.language English -
dc.publisher Cold Spring Harbor Laboratory Press -
dc.title Balanced actions of protein synthesis and degradation in memory formation -
dc.type Article -
dc.identifier.doi 10.1101/lm.048785.118 -
dc.identifier.wosid 000486298800002 -
dc.identifier.scopusid 2-s2.0-85071586286 -
dc.type.local Article(Overseas) -
dc.type.rims ART -
dc.description.journalClass 1 -
dc.contributor.nonIdAuthor Kaang, Bong-Kiun -
dc.identifier.citationVolume 26 -
dc.identifier.citationNumber 9 -
dc.identifier.citationStartPage 299 -
dc.identifier.citationEndPage 306 -
dc.identifier.citationTitle Learning and Memory -
dc.type.journalArticle Review -
dc.description.isOpenAccess Y -
dc.subject.keywordPlus LONG-TERM POTENTIATION -
dc.subject.keywordPlus MENTAL-RETARDATION PROTEIN -
dc.subject.keywordPlus FRAGILE-X -
dc.subject.keywordPlus SYNAPTIC PLASTICITY -
dc.subject.keywordPlus EPIGENETIC MECHANISMS -
dc.subject.keywordPlus MOLECULAR-MECHANISM -
dc.subject.keywordPlus NEUROTROPHIC FACTOR -
dc.subject.keywordPlus NEGATIVE REGULATOR -
dc.subject.keywordPlus AXONAL-TRANSPORT -
dc.subject.keywordPlus SENSORY NEURONS -
Files in This Item:

There are no files associated with this item.

Appears in Collections:
ETC 1. Journal Articles


  • twitter
  • facebook
  • mendeley

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.