Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Lee, Seungmin | - |
dc.contributor.author | Kim, Jin-young | - |
dc.contributor.author | Kim, Junyoung | - |
dc.contributor.author | Hoshiar, Ali Kafash | - |
dc.contributor.author | Park, Jongeon | - |
dc.contributor.author | Lee, Sunkey | - |
dc.contributor.author | Kim, Jonghyun | - |
dc.contributor.author | Pane, Salvador | - |
dc.contributor.author | Nelson, Bradley J. | - |
dc.contributor.author | Choi, Hongsoo | - |
dc.date.accessioned | 2020-03-20T10:54:28Z | - |
dc.date.available | 2020-03-20T10:54:28Z | - |
dc.date.created | 2020-03-20 | - |
dc.date.issued | 2020-04 | - |
dc.identifier.issn | 2192-2640 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/11575 | - |
dc.description.abstract | A needle-type microrobot (MR) for targeted drug delivery is developed to stably deliver drugs to a target microtissue (MT) for a given period time without the need for an external force after affixing. The MRs are fabricatedby 3D laser lithography and nickel (Ni)/titanium oxide (TiO2) layers are coated by physical vapor deposition. The translational velocity of the MR is 714 µm s−1 at 20 mT and affixed to the target MT under the control of a rotating magnetic field. The manipulability of the MR is shown by using both manual and automatic controls. Finally, drug release from the paclitaxel-loaded MR is characterized to determine the efficiency of targeted drug delivery. This study demonstrates the utility of the proposed needle-type MR for targeted drug delivery to MT with various flow rates in vitro physiological fluidic environments. © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim | - |
dc.language | English | - |
dc.publisher | John Wiley and Sons Ltd | - |
dc.title | A Needle-Type Microrobot for Targeted Drug Delivery by Affixing to a Microtissue | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/adhm.201901697 | - |
dc.identifier.wosid | 000517782600001 | - |
dc.identifier.scopusid | 2-s2.0-85081025968 | - |
dc.identifier.bibliographicCitation | Advanced Healthcare Materials, v.9, no.7, pp.1901697 | - |
dc.description.isOpenAccess | FALSE | - |
dc.subject.keywordAuthor | fixation | - |
dc.subject.keywordAuthor | magnetic manipulation | - |
dc.subject.keywordAuthor | microrobots | - |
dc.subject.keywordAuthor | targeted drug delivery | - |
dc.subject.keywordAuthor | drug delivery | - |
dc.subject.keywordPlus | ARTIFICIAL BACTERIAL FLAGELLA | - |
dc.subject.keywordPlus | FABRICATION | - |
dc.subject.keywordPlus | TIME | - |
dc.identifier.url | https://onlinelibrary.wiley.com/cms/asset/120d5e8d-aba2-48f3-a53b-0f3f29bfe090/adhm202070019-gra-0001-m.jpg | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1901697 | - |
dc.citation.title | Advanced Healthcare Materials | - |
dc.citation.volume | 9 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering; Science & Technology - Other Topics; Materials Science | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical; Nanoscience & Nanotechnology; Materials Science, Biomaterials | - |
dc.type.docType | Article | - |
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