Center for Synapse Diversity and Specificity57
Jaewon Ko currently directs the Center for Synapse Diversity and Specificity (CSDS) at DGIST. He is interested in understanding the synaptic mechanisms underlying how neural circuits are wired, shaped, and modulated during development and in adulthood. His work focuses on (1) the roles of synaptic cell-adhesion molecules (CAMs) in shaping specific synapse properties in a defined neural circuit, (2) pre- and postsynaptic signaling mechanisms responsible for CAM-mediated synapse diversity and specificity, and (3) pathophysiological mechanisms of neurological disorders encompassing impaired neural circuit properties.
The CSDS aims address these fundamental neuroscientific questions by employing multiple, interdisciplinary approaches ranging from biochemical and biophysical studies to physiological and behavioral analyses of mutant mice deficient in key synaptic adhesion molecules and their associated proteins.
Advisor Professor : Ko, Jaewon
Center for Synapse Diversity and Specificity Homepage
The CSDS aims address these fundamental neuroscientific questions by employing multiple, interdisciplinary approaches ranging from biochemical and biophysical studies to physiological and behavioral analyses of mutant mice deficient in key synaptic adhesion molecules and their associated proteins.
Advisor Professor : Ko, Jaewon
Center for Synapse Diversity and Specificity Homepage
Subject
- LAR-RPTPS 7
- synaptic adhesion 7
- COMPLEXES 6
- EXPRESSION 6
- INHIBITION 6
- PLASTICITY 6
- BINDING 5
- NEUROLIGINS 5
- PTP-SIGMA 5
- synapse 5
Co-Author(s)
Related Keyword
Recent Submissions
- Development of New IL-1R Antagonists with Improved Anti-inflammatory Efficacy
- Autism-associated ARHGEF9 variants impair GABAergic synapses and ultrasonic communication by reducing gephyrin phosphorylation
- The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate receptor functions
- EphB2 receptor tyrosine kinase-mediated excitatory synaptic functions are negatively modulated by MDGA2
- IQSEC3의 선택적 조절을 통한 공포 기억 장애 모델 및 그 제조방법
