Cited 2 time in webofscience Cited 3 time in scopus

Rapidly-Customizable, Scalable 3D-Printed Wireless Optogenetic Probes for Versatile Applications in Neuroscience

Title
Rapidly-Customizable, Scalable 3D-Printed Wireless Optogenetic Probes for Versatile Applications in Neuroscience
Authors
Lee, JuhyunParker, Kyle E.Kawakami, ChinatsuKim, Jenny R.Qazi, RazaYea, JunwooZhang, ShunKim, Choong YeonBilbily, JohnXiao, JianliangJang, Kyung-InMcCall, Jordan G.Jeong, Jae-Woong
DGIST Authors
Lee, Juhyun; Parker, Kyle E.; Kawakami, Chinatsu; Kim, Jenny R.; Qazi, Raza; Yea, Junwoo; Zhang, Shun; Kim, Choong Yeon; Bilbily, John; Xiao, Jianliang; Jang, Kyung-In; McCall, Jordan G.; Jeong, Jae-Woong
Issue Date
2020-11
Citation
Advanced Functional Materials, 30(46), 2004285
Type
Article
Article Type
Article
Author Keywords
3D printingmicrofabricationneural probesoptogeneticswireless probes
Keywords
OPTOELECTRONICSPHARMACOLOGYFABRICATIONNEURONSDEVICESFIBERS
ISSN
1616-301X
Abstract
Optogenetics is an advanced neuroscience technique that enables the dissection of neural circuitry with high spatiotemporal precision. Recent advances in materials and microfabrication techniques have enabled minimally invasive and biocompatible optical neural probes, thereby facilitating in vivo optogenetic research. However, conventional fabrication techniques rely on cleanroom facilities, which are not easily accessible and are expensive to use, making the overall manufacturing process inconvenient and costly. Moreover, the inherent time-consuming nature of current fabrication procedures impede the rapid customization of neural probes in between in vivo studies. Here, a new technique stemming from 3D printing technology for the low-cost, mass production of rapidly customizable optogenetic neural probes is introduced. The 3D printing production process, on-the-fly design versatility, and biocompatibility of 3D printed optogenetic probes as well as their functional capabilities for wireless in vivo optogenetics is detailed. Successful in vivo studies with 3D printed devices highlight the reliability of this easily accessible and flexible manufacturing approach that, with advances in printing technology, can foreshadow its widespread applications in low-cost bioelectronics in the future. © 2020 Wiley-VCH GmbH
URI
http://hdl.handle.net/20.500.11750/12666
DOI
10.1002/adfm.202004285
Publisher
Wiley-VCH Verlag
Related Researcher
  • Author Jang, Kyung-In Bio-integrated Electronics Lab
  • Research Interests Extreme mechanics; Stand-alone electronics; Heterogeneous materials; Biocompatible interfaces
Files:
There are no files associated with this item.
Collection:
Department of Robotics EngineeringBio-integrated Electronics Lab1. Journal Articles


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