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Molecular principles of mammalian GABAergic synapse formation

Title
Molecular principles of mammalian GABAergic synapse formation
Authors
Ko, Jaewon
DGIST Authors
Ko, Jaewon
Issue Date
2019-05-30
Citation
UK-Korea Research Conference
Type
Conference
Abstract
Synaptic adhesion proteins are central synapse organizers that serve to control the establishment, maintenance, refinement, and even elimination of neural circuits. Neuroligin-2 is a key factor in mammalian GABAergic synapse development that binds to presynaptic neurexins and the postsynaptic scaffold, gephyrin. In this talk, Professor Ko will discuss his recent studies on additional neuroligin-2–interacting cell-surface proteins and their synaptic functions, which have been actively investigated in his laboratory. Intriguingly, all of these proteins have been implicated in various brain disorders. Collectively, these studies have contributed to expanding our current understanding of how mammalian GABAergic synapses are molecularly organized
URI
http://hdl.handle.net/20.500.11750/14448
Publisher
Royal Society-IBS
Related Researcher
  • Author Ko, Jaewon Laboratory of Synapse Formation and Function
  • Research Interests Synapse Formation and Function; Neural Circuits; 뇌질환; animal model
Files:
There are no files associated with this item.
Collection:
Department of Brain SciencesLaboratory of Synapse Formation and Function2. Conference Papers


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