Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 최한경 | - |
| dc.contributor.author | Seree Park | - |
| dc.date.accessioned | 2022-03-07T16:00:25Z | - |
| dc.date.available | 2022-03-07T16:00:25Z | - |
| dc.date.issued | 2022 | - |
| dc.identifier.uri | http://dgist.dcollection.net/common/orgView/200000593842 | en_US |
| dc.identifier.uri | http://hdl.handle.net/20.500.11750/16298 | - |
| dc.description | Oxytocin, Primary cilia, Ift88, Social recognition, Fiber photometry | - |
| dc.description.statementofresponsibility | N | - |
| dc.description.tableofcontents | I. Introduction 1 II. Materials and Methods 3 III. Results 9 3.1 Knockdown of Ift88 in PVN-Oxt neurons with shRNA reduced cilia length 9 3.2 Adult-onset inhibition of ciliogenesis with shIft88 in PVN-Oxt neurons selectively disrupted social recognition and memory 10 3.3 Ift88 knockdown in adult PVN-Oxt neurons did not change metabolic phenotype 11 3.4 Postnatal Ift88 knockdown in PVN-Oxt neurons did not alter axonal projection 12 3.5 Ciliary dysgenesis in adult PVN-Oxt neurons increased spontaneous EPSCs 13 3.6 PVN-Oxt neurons are activated by social stimuli, especially on social novelty 14 3.7 Cilia mutant PVN-Oxt neurons showed different neuronal response 16 IV. Discussion 37 V. References 41 |
- |
| dc.format.extent | 46 | - |
| dc.language | eng | - |
| dc.publisher | DGIST | - |
| dc.subject | Oxytocin, Primary cilia, Ift88, Social recognition, Fiber photometry | - |
| dc.title | Knockdown of Primary Ciliary Component Gene in Hypothalamic Paraventricular Nucleus Oxytocin Neurons Impairs Social Behavior | - |
| dc.type | Thesis | - |
| dc.identifier.doi | 10.22677/thesis.200000593842 | - |
| dc.description.degree | Master | - |
| dc.contributor.department | Brain and Cognitive Sciences | - |
| dc.contributor.coadvisor | Jeongyeon Kim | - |
| dc.date.awarded | 2022/02 | - |
| dc.publisher.location | Daegu | - |
| dc.description.database | dCollection | - |
| dc.citation | XT.BM 박54 202202 | - |
| dc.date.accepted | 1/21/22 | - |
| dc.contributor.alternativeDepartment | 뇌인지과학전공 | - |
| dc.embargo.liftdate | 20260228 | - |
| dc.contributor.affiliatedAuthor | Seree Park | - |
| dc.contributor.affiliatedAuthor | Han Kyoung Choe | - |
| dc.contributor.affiliatedAuthor | Jeongyeon Kim | - |
| dc.contributor.alternativeName | 박세리 | - |
| dc.contributor.alternativeName | Han Kyoung Choe | - |
| dc.contributor.alternativeName | 김정연 | - |
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