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Meta-Selective C-H Functionalization of Arylsilanes Using a Silicon Tethered Directing Group
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Title
Meta-Selective C-H Functionalization of Arylsilanes Using a Silicon Tethered Directing Group
Issued Date
2022-07
Citation
Bang, Jaehan. (2022-07). Meta-Selective C-H Functionalization of Arylsilanes Using a Silicon Tethered Directing Group. Organic Letters, 24(28), 5181–5185. doi: 10.1021/acs.orglett.2c02015
Type
Article
Keywords
LEWIS-ACIDACTIVATIONOLEFINATIONTEMPLATEBONDSARENESSILYLATIONTRACELESSMECHANISMARYLATION
ISSN
1523-7060
Abstract
We describe meta-selective C-H functionalization of arylsilanes using a Si-tethered directing group. The current method enables a selective alkenylation of arenes bearing a variety of functional groups, and several electron-deficient olefins are also applicable as coupling partners. Further functional group transformations of the silicon-tethered directing group provide multi substituted arenes efficiently.
URI
http://hdl.handle.net/20.500.11750/17129
DOI
10.1021/acs.orglett.2c02015
Publisher
American Chemical Society
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