Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Lee, Hye Hyeon | - |
dc.contributor.author | Han, Min Ho | - |
dc.contributor.author | Hwang, Hye Jin | - |
dc.contributor.author | Kim, Gi-Young | - |
dc.contributor.author | Moon, Sung-Kwon | - |
dc.contributor.author | Hyun, Jin-Won | - |
dc.contributor.author | Kim, Wun-Jae | - |
dc.contributor.author | Choi, Yung Hyun | - |
dc.date.available | 2017-07-11T06:00:43Z | - |
dc.date.created | 2017-04-10 | - |
dc.date.issued | 2015-02 | - |
dc.identifier.issn | 1107-3756 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/2937 | - |
dc.description.abstract | Diallyl trisulfide (DATS; di-2-propen-1-yl trisulfide) is an organic polysulfide compound found in garlic and other allium vegetables. Although certain studies have demonstrated that DATS possesses strong anti-inflammatory activity, the underlying molecular mechanisms remain largely unresolved. In the present study, the anti-inflammatory potential of DATS was investigated using the murine macrophage RAW 264.7 cell model. At non-toxic concentrations, DATS inhibited the production of nitric oxide (NO) and prostaglandin E |
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dc.publisher | Spandidos Publications | - |
dc.title | Diallyl trisulfide exerts anti-inflammatory effects in lipopolysaccharide-stimulated RAW 264.7 macrophages by suppressing the Toll-like receptor 4/nuclear factor-kappa B pathway | - |
dc.type | Article | - |
dc.identifier.doi | 10.3892/ijmm.2014.2036 | - |
dc.identifier.scopusid | 2-s2.0-84919680292 | - |
dc.identifier.bibliographicCitation | International Journal of Molecular Medicine, v.35, no.2, pp.487 - 495 | - |
dc.subject.keywordAuthor | diallyl trisulfide | - |
dc.subject.keywordAuthor | inflammation | - |
dc.subject.keywordAuthor | nuclear factor-kappa B | - |
dc.subject.keywordAuthor | Toll-like receptor 4 | - |
dc.subject.keywordPlus | GARLIC ORGANOSULFUR COMPOUNDS | - |
dc.subject.keywordPlus | RAW-264.7 MACROPHAGES | - |
dc.subject.keywordPlus | MOLECULAR-MECHANISMS | - |
dc.subject.keywordPlus | SIGNAL-TRANSDUCTION | - |
dc.subject.keywordPlus | INFLAMMATION | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | TLR4 | - |
dc.subject.keywordPlus | ACTIVATION | - |
dc.subject.keywordPlus | INDUCTION | - |
dc.subject.keywordPlus | CANCER | - |
dc.citation.endPage | 495 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 487 | - |
dc.citation.title | International Journal of Molecular Medicine | - |
dc.citation.volume | 35 | - |
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