Title

Practical Deuteration of Organic Compounds by Thiyl Radical Catalysis

Alternative Title

황 중심 라디칼 촉매를 이용한 유기 화합물의 실용적 중수소화

DGIST Authors

Jiin Lee ; Sunggi Lee ; Byunghyuck Jung

Advisor

이성기

Co-Advisor(s)

Byunghyuck Jung

Issued Date

2025

Awarded Date

2025-08-01

Type

Thesis

Description

deuteration, thiyl radical, hydrogen atom transfer, halogen atom transfer

Table Of Contents

Abstract i
List of Contents ii
Ⅰ. Chapter 1. Dehalogenative deuteration of alkyl and aryl bromides by thiyl radical catalysis
1. Introduction 1
2. Result & discussion 4
2.1 Reaction optimization 4
2.2 Control experiment 7
2.3 Substate scope 7
2.4 Mechanistic study 10
2.5 Synthetic utility 11
3. Conclusion 13
4. Experimental data 14
4.1 General consideration 14
4.2 Experimental section 15
4.3 UV/Vis absorption spectroscopy 43
5. References 48
Ⅱ. Chapter 2. Decarbonylative iterative deuteration of alkyl aldehydes by thiyl radical catalysis
1. Introduction 52
2. Result & discussion 55
2.1 Reaction optimization 55
2.2 Substate scope 61
2.3 Synthetic application 62
3. Conclusion 65
4. Experimental data 66
4.1 General consideration 66
4.2 Experimental section 67
5. References 76
요약문 79

URI

https://scholar.dgist.ac.kr/handle/20.500.11750/59801
http://dgist.dcollection.net/common/orgView/200000891848

DOI

10.22677/THESIS.200000891848

Degree

Doctor

Department

Department of Physics and Chemistry

Publisher

DGIST

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