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Modulation mechanisms of voltage-gated calcium channels
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dc.contributor.author Park, Cheon Gyu -
dc.contributor.author Suh, Byung Chang -
dc.date.accessioned 2018-08-29T05:52:06Z -
dc.date.available 2018-08-29T05:52:06Z -
dc.date.created 2018-08-22 -
dc.date.issued 2018-04 -
dc.identifier.issn 2468-8673 -
dc.identifier.uri http://hdl.handle.net/20.500.11750/9240 -
dc.description.abstract Voltage-gated calcium (CaV) channels mediate diverse essential physiological functions through membrane depolarization-induced Ca2+ influx. Malfunction of CaV channels causes various pathophysiological disorders. A wide range of cellular signals, including phosphoinositides, auxiliary CaV β subunits, Ca2+/calmodulin, and phosphorylation, are crucial for finely controlling the activity of CaV channels. Various interacting proteins, such as 14-3-3 protein, densin, and stac3, are also important in regulating the surface expression of CaV channels. Here, this review provides recent advances in the regulatory mechanisms of CaV channel gating and trafficking. © 2018 Elsevier Ltd -
dc.language English -
dc.publisher Elsevier Ltd -
dc.title Modulation mechanisms of voltage-gated calcium channels -
dc.type Article -
dc.identifier.doi 10.1016/j.cophys.2018.01.005 -
dc.identifier.wosid 000471278700012 -
dc.identifier.scopusid 2-s2.0-85051031208 -
dc.identifier.bibliographicCitation Park, Cheon Gyu. (2018-04). Modulation mechanisms of voltage-gated calcium channels. Current Opinion in Physiology, 2, 77–83. doi: 10.1016/j.cophys.2018.01.005 -
dc.description.isOpenAccess FALSE -
dc.subject.keywordPlus CA2+ CHANNEL -
dc.subject.keywordPlus BETA-2E SUBUNIT -
dc.subject.keywordPlus PROTEIN-KINASE -
dc.subject.keywordPlus SKELETAL-MUSCLE -
dc.subject.keywordPlus CA(V)1.2 -
dc.subject.keywordPlus PHOSPHORYLATION -
dc.subject.keywordPlus TRAFFICKING -
dc.subject.keywordPlus PIP2 -
dc.subject.keywordPlus PHOSPHOINOSITIDES -
dc.subject.keywordPlus ALPHA(2)DELTA -
dc.citation.endPage 83 -
dc.citation.startPage 77 -
dc.citation.title Current Opinion in Physiology -
dc.citation.volume 2 -
dc.description.journalRegisteredClass scopus -
dc.relation.journalResearchArea Physiology -
dc.relation.journalWebOfScienceCategory Physiology -
dc.type.docType Review -
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서병창
Suh, Byung-Chang서병창

Department of Brain Sciences

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