서병창
Suh, Byung-Chang학력
- 1994 ~ 1997포항공과대학교 박사
- 1992 ~ 1994포항공과대학교 석사
- 1987 ~ 1991서울대학교 학사
경력
- 2004 ~ 2011Univ. of Washington / 연구조교수
- 2001 ~ 2004Univ. of Washington / 박사후연구원
- 1997 ~ 2002포항공대 기초과학연구소 / 박사후연구원
수상실적
- 2025 총장표창 / DGIST
- 2023 총장표창 / DGIST
- 2016 공로상 / DGIST
연구실 소개
- Laboratory of Brain Signal and Synapse Research
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Our research goal is to determine the molecular mechanism and biophysical properties of ion channel modulation, neuronal excitability and synaptic transmission. We'd fundamentally like to examine the functional significance of membrane biology in various neuronal diseases like epilepsy, pain, psychiatric disorders, channelopathies and etc.
Neuronal disordersExaminations on functional significance of membrane biology in various neuronal disorders
Receptor modulationMetabotropic & ionotropic receptor modulation of neuronal excitability and synaptic transmission
Ion channelsMechanism and biophysical properties of ion channels
PhosphoinositidesIon channel modulation by membrane lipid (phosphoinositiedes) metabolism
ElectrophysiologyMeasurements of voltage change or electric current on a wide variety of scales from ion channels to the brain
Signal tansductionNeurotransmission caused by signal transduction (the essential process for communication between two neurons)
- "Activation of TMEM16E scramblase induces ligand independent growth factor receptor signaling and macropinocytosis for membrane repair", Kim, Jung-Eun. (2025-01). Activation of TMEM16E scramblase induces ligand independent growth factor receptor signaling and macropinocytosis for membrane repair. Communications Biology, 8(1). doi: 10.1038/s42003-025-07465-6
- "A FMRFamide-like neuropeptide FLP-12 signaling regulates head locomotive behaviors in Caenorhabditis elegans", Kim, Do-Young. (2024-12). A FMRFamide-like neuropeptide FLP-12 signaling regulates head locomotive behaviors in Caenorhabditis elegans. Molecules and Cells, 47(12), 1–13. doi: 10.1016/j.mocell.2024.100124
- "The plasma membrane inner leaflet PI(4,5)P2 is essential for the activation of proton-activated chloride channels", Ko, Woori. (2024-08). The plasma membrane inner leaflet PI(4,5)P2 is essential for the activation of proton-activated chloride channels. Nature Communications, 15(1). doi: 10.1038/s41467-024-51400-y
- "Molecular and cellular basis of sodium sensing in Drosophila labellum", Asefa, Wayessa Rahel. (2024-07). Molecular and cellular basis of sodium sensing in Drosophila labellum. iScience, 27(7). doi: 10.1016/j.isci.2024.110248
- "ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes", Lee, Hyein. (2023-10). ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes. Cell Reports, 42(10). doi: 10.1016/j.celrep.2023.113183
- "Differential regulation of current kinetics by the β subunits in N-type calcium channel", Woo, Jin-Nyeong. (2025-02-18). Differential regulation of current kinetics by the β subunits in N-type calcium channel. Biophysical Society Annual Meeting (BPS 2025), 451A-451A.
- "Two-step structural changes in M3 muscarinic receptor activation rely on the coupled G protein cycle", 2023 Annual Biophysical Society Meeting, pp.15a
- "Allosteric Modulation of Ca2+-Activated Cl- Channles TMEM16A by PIP2 and CAMKII", Ko, Woori. (2019-03-04). Allosteric Modulation of Ca2+-Activated Cl- Channles TMEM16A by PIP2 and CAMKII. 63rd Annual Meeting of the Biophysical Society, 222A-222A. doi: 10.1016/j.bpj.2018.11.1223
- "Molecular Mechanism of Voltage-Gated Ca2+ Channel Regulation by Membrane PIP2", Park, Cheon-Gyu. (2019-03-03). Molecular Mechanism of Voltage-Gated Ca2+ Channel Regulation by Membrane PIP2. 63rd Annual Meeting of the Biophysical Society, 41A-41A. doi: 10.1016/j.bpj.2018.11.264
- "Ethanol Increases Neuronal Firing by Regulating PI(4,5)P2 Sensitivity of M-Type K+ Channels", 62nd Annual Meeting of the Biophysical Society, pp.121A
연구 뉴스
- An important secret to preventing cell damage: The working principle of PAC channels has been revealed! 2024-09-03
- 세포 손상을 막는 중요한 비밀: PAC 채널의 작동 원리 밝혀내다! 2024-08-22
- Joint Research Team between DGIST, Kyungpook National University, and KIOM Discovered Pathological Function of Alzheimer's Disease Risk Factor (APOE4) and Suggested New Treatment Options 2023-12-20
- DGIST-경북대-KIOM 공동연구팀, 알츠하이머 치매 원인 인자(APOE4)의 병리적 기능 발견으로 새로운 치료 방안 제시 2023-10-19
- Development of a biosensor for real time detection of the G-protein molecular switch in our body 2023-03-31
연구분야
미래유망 신기술(6T)