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바이오 의학 응용을 위한 전자기 구동소프트 하이드로겔 마이크로로봇

Title
바이오 의학 응용을 위한 전자기 구동소프트 하이드로겔 마이크로로봇
Translated Title
Electromagnetically Actuated Soft Hydrogel Microrobots for Biomedical Applications
Authors
최현철이효룡고광준박종오박석호
DGIST Authors
박석호
Issue Date
2019-02
Citation
Journal of Institute of Control, Robotics and Systems, 25(2), 156-162
Type
Article
Article Type
Article
Author Keyword
Drug delivery; Electromagnetic actuation system; Hydrogel; Manipulation; Medical robot; Microrobot; NIPAAM
Keyword
Data communication equipment; Drug delivery; Electromechanical actuators; Hydrogels; Medical applications; Nanomagnetics; Nanoparticles; Targeted drug delivery; Electromagnetic actuation; Manipulation; Medical robots; Micro robots; NIPAAM; Controlled drug delivery
ISSN
1976-5622
Abstract
This paper introduces electromagnetically actuated biomedical microrobots using external stimulus responsive hydrogels. We briefly summarize several research trends using representative magnetic actuated hydrogel microrobots developed to date and introduce our three developed types of magnetic actuated hydrogel microrobots. First, we propose a selective microrobots control method using microclampers consisting of temperature-responsive hydrogel (NIPAAM) blocks and microheaters. Using the selective microrobots control method, multiple microrobots can be independently controlled by an electromagnetic actuation (EMA) system. Second, we developed a self-folding magnetically driven microrobot in which a layer containing magnetic nanoparticles (MNPs) and a temperature-responsive hydrogel layer are laminated. The motion of the magnetically driven microrobot is controlled precisely using magnetic field control and the microrobot performs self-(un)folding motion due to the temperature change. Additionally, the microrobot is able to grab a bead containing a drug and to manipulate it precisely to a desired position. Finally, we developed a spring-shaped hydrogel (NIPAAM) microrobot using drugs and MNPs. By using an integrated system containing an EMA system and a near-infra-red (NIR) light generating device, we demonstrated that the spring-type hydrogel microrobot can move to a desired position and actively release the loaded drug. Thus, it is shown that a variety of magnetically actuated hydrogel microrobots were developed and further in-depth studies are necessary for the development and use of these microrobots in biomedical applications. © ICROS 2019.
URI
http://hdl.handle.net/20.500.11750/9686
DOI
10.5302/J.ICROS.2019.18.0201
Publisher
Institute of Control, Robotics and Systems
Related Researcher
  • Author Park, Sukho Multiscale Biomedical Robotics Laboratory
  • Research Interests Biomedical Micro/Nano Robotics; Biomedical Devices and Instruments
Files:
There are no files associated with this item.
Collection:
Department of Robotics EngineeringMultiscale Biomedical Robotics Laboratory1. Journal Articles


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