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Article
Autism-associated ARHGEF9 variants impair GABAergic synapses and ultrasonic communication by reducing gephyrin phosphorylation
  • Jung, Hyeji ; 
  • Kim, Byeongchan ; 
  • Jang, Gyubin ; 
  • Lee, Hyojeong ; 
  • Kim, Younghye ; 
  • Kim, Hyeonho ; 
  • Lee, Heaji ; 
  • Kim, Dongwook ; 
  • Yang, Yeji ; 
  • Jeong, Woo Chan ; 
    • et al
  • 2026-03
  • MOLECULAR PSYCHIATRY, v.31, no.3, pp.1757 - 1773
  • SPRINGERNATURE
  • View : 190
  • Download : 0
Article
CASKIN2 mediates PTPσ-orchestrated transsynaptic mechanisms at excitatory synapses
  • Han, Kyung Ah ; 
  • Jang, Gyubin ; 
  • Lee, Hee-Yoon ; 
  • Kim, Byeongchan ; 
  • Kanato, Tayo ; 
  • Vas, Virág ; 
  • Buday, László ; 
  • Liu, Xinran ; 
  • Choi, Se-Young ; 
  • Um, Ji Won ; 
    • et al
  • 2025-11
  • Proceedings of the National Academy of Sciences of the United States of America, v.122, no.46
  • National Academy of Sciences
  • View : 110
  • Download : 0

Development of New IL-1R Antagonists with Improved Anti-inflammatory Efficacy

Article
Development of New IL-1R Antagonists with Improved Anti-inflammatory Efficacy
  • Kang, Mooseok ; 
  • Lee, Ae-Ree ; 
  • Jung, Hyeji ; 
  • Jang, Gyubin ; 
  • Kim, Byeongchan ; 
  • Yoon, Sung-Hyun ; 
  • Yu, Je-Wook ; 
  • Ko, Jaewon ; 
  • Um, Ji Won ; 
  • Chang, Iksoo
  • 2026-01
  • Theranostics, v.16, no.5, pp.2561 - 2575
  • Ivyspring International Publisher
  • View : 183
  • Download : 79
Article
EphB2 receptor tyrosine kinase-mediated excitatory synaptic functions are negatively modulated by MDGA2
  • Kim, Hyeonho ; 
  • Jeon, Younghyeon ; 
  • Kim, Seunghye ; 
  • Guo, Yuxuan ; 
  • Kim, Dongwook ; 
  • Jang, Gyubin ; 
  • Brasch, Julia ; 
  • Um, Ji Won ; 
  • Ko, Jaewon
  • 2025-07
  • Kim, Hyeonho. (2025-07). EphB2 receptor tyrosine kinase-mediated excitatory synaptic functions are negatively modulated by MDGA2. Progress in Neurobiology, 250. doi: 10.1016/j.pneurobio.2025.102772
  • Elsevier
  • View : 474
  • Download : 0
Article
MDGA2 homozygous loss-of-function variants cause developmental and epileptic encephalopathy
  • Morsy, Heba ; 
  • Kim, Hyeonho ; 
  • Jang, Gyubin ; 
  • Zaki, Maha S. ; 
  • Severino, Mariasavina ; 
  • Abdelrazek, Ibrahim M. ; 
  • Hussien, Haytham ; 
  • Self, Eleanor ; 
  • Albaradie, Raidah Saleem ; 
  • Bakur, Khadija H. ; 
    • et al
  • 2026-02
  • American Journal of Human Genetics, v.113, no.2, pp.1 - 12
  • University of Chicago Press
  • View : 125
  • Download : 0
Article
MDGAs perform activity- dependent synapse type- specific suppression via distinct extracellular mechanisms
  • Kim, Seungjoon ; 
  • Jang, Gyubin ; 
  • Kim, Hyeonho ; 
  • Lim, Dongseok ; 
  • Han, Kyung Ah ; 
  • Um, Ji Won ; 
  • Ko, Jaewon
  • 2024-06
  • Proceedings of the National Academy of Sciences of the United States of America, v.121, no.26
  • National Academy of Sciences
  • View : 524
  • Download : 0
Article
SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice
  • Chehadeh, Salima El ; 
  • Han, Kyung Ah ; 
  • Kim, Dongwook ; 
  • Jang, Gyubin ; 
  • Bakhtiari, Somayeh ; 
  • Lim, Dongseok ; 
  • Kim, Hee Young ; 
  • Kim, Jinhu ; 
  • Kim, Hyeonho ; 
  • Wynn, Julia ; 
    • et al
  • 2022-07
  • Chehadeh, Salima El. (2022-07). SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice. Nature Communications, 13(1). doi: 10.1038/s41467-022-31566-z
  • Nature Publishing Group
  • View : 769
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Specification of neural circuit architecture shaped by context-dependent patterned LAR-RPTP microexons

Article
Specification of neural circuit architecture shaped by context-dependent patterned LAR-RPTP microexons
  • Han, Kyung Ah ; 
  • Yoon, Taek Han ; 
  • Kim, Jinhu ; 
  • Lee, Jusung ; 
  • Lee, Ju Yeon ; 
  • Jang, Gyubin ; 
  • Um, Ji Won ; 
  • Kim, Jong Kyoung ; 
  • Ko, Jaewon
  • 2024-03
  • Han, Kyung Ah. (2024-03). Specification of neural circuit architecture shaped by context-dependent patterned LAR-RPTP microexons. Nature Communications, 15(1), 1624. doi: 10.1038/s41467-024-45695-0
  • Nature Publishing Group
  • View : 469
  • Download : 172

The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate receptor functions

Article
The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate receptor functions
  • Jung, Hyeji ; 
  • Kim, Byeongchan ; 
  • Jang, Gyubin ; 
  • Kim, Hyeonho ; 
  • Lee, Ae-Ree ; 
  • Yoon, Sung-Hyun ; 
  • Lee, Kyung-Seo ; 
  • Hyun, Gaeun ; 
  • Kim, Younghye ; 
  • Ko, Jaewon ; 
    • et al
  • 2025-05
  • Cell Reports, v.44, no.5
  • Cell Press
  • View : 503
  • Download : 198

Thermodynamic modulation of gephyrin condensation by inhibitory synapse components

Article
Thermodynamic modulation of gephyrin condensation by inhibitory synapse components
  • Lee, Gyehyun ; 
  • Kim, Seungjoon ; 
  • Hwangd, Da-Eun ; 
  • Eomd, Yu-Gon ; 
  • Jang, Gyubin ; 
  • Park, Hye Yoon ; 
  • Choi, Jeong-Mo ; 
  • Ko, Jaewon ; 
  • Shin, Yongdae
  • 2024-03
  • Lee, Gyehyun. (2024-03). Thermodynamic modulation of gephyrin condensation by inhibitory synapse components. Proceedings of the National Academy of Sciences of the United States of America, 121(12). doi: 10.1073/pnas.2313236121
  • National Academy of Sciences
  • View : 463
  • Download : 213
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