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Distinct Developmental Features of Olfactory Bulb Interneurons
- Title
- Distinct Developmental Features of Olfactory Bulb Interneurons
- Authors
- Kim, Jae Yeon; Choe, Jiyun; Moon, Cheil
- DGIST Authors
- Kim, Jae Yeon; Choe, Jiyun; Moon, Cheil
- Issue Date
- 2020-03
- Citation
- Molecules and Cells, 43(3), 215-221
- Type
- Article
- Article Type
- Article
- Author Keywords
- development; diversity; interneuron; olfactory bulb; spatio-temporal specification
- Keywords
- NEOCORTICAL INTERNEURONS; GABAERGIC INTERNEURONS; CORTICAL INTERNEURONS; ADULT NEUROGENESIS; LAMINAR FATE; BIRTH-DATE; NEURONS; INTEGRATION; FOREBRAIN; ORIGIN
- ISSN
- 1016-8478
- Abstract
- The olfactory bulb (OB) has an extremely higher proportionof interneurons innervating excitatory neurons than otherbrain regions, which is evolutionally conserved across species.Despite the abundance of OB interneurons, little is knownabout the diversification and physiological functions ofOB interneurons compared to cortical interneurons. In thisreview, an overview of the general developmental processof interneurons from the angles of the spatial and temporalspecifications was presented. Then, the distinct featuresshown exclusively in OB interneurons development andmolecular machinery recently identified were discussed.Finally, we proposed an evolutionary meaning for thediversity of OB interneurons.
- URI
- http://hdl.handle.net/20.500.11750/11658
- DOI
- 10.14348/molcells.2020.0033
- Publisher
- 한국분자세포생물학회
- Related Researcher
-
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Moon, Cheil
Laboratory of Chemical Senses
-
Research Interests
Brain convergent science based on chemical senses; olfaction; 감각신경계 기반 뇌융합과학; 후각 신경계
- Files:
-
- Collection:
- Department of Brain SciencesLaboratory of Chemical Senses1. Journal Articles
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