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Distinct Developmental Features of Olfactory Bulb Interneurons

Title
Distinct Developmental Features of Olfactory Bulb Interneurons
Authors
Kim, Jae YeonChoe, JiyunMoon, Cheil
DGIST Authors
Moon, Cheil
Issue Date
2020-03
Citation
Molecules and Cells, 43(3), 215-221
Type
Article
Article Type
Article
Author Keywords
developmentdiversityinterneuronolfactory bulbspatio-temporal specification
Keywords
NEOCORTICAL INTERNEURONSGABAERGIC INTERNEURONSCORTICAL INTERNEURONSADULT NEUROGENESISLAMINAR FATEBIRTH-DATENEURONSINTEGRATIONFOREBRAINORIGIN
ISSN
1016-8478
Abstract
The olfactory bulb (OB) has an extremely higher proportionof interneurons innervating excitatory neurons than otherbrain regions, which is evolutionally conserved across species.Despite the abundance of OB interneurons, little is knownabout the diversification and physiological functions ofOB interneurons compared to cortical interneurons. In thisreview, an overview of the general developmental processof interneurons from the angles of the spatial and temporalspecifications was presented. Then, the distinct featuresshown exclusively in OB interneurons development andmolecular machinery recently identified were discussed.Finally, we proposed an evolutionary meaning for thediversity of OB interneurons.
URI
http://hdl.handle.net/20.500.11750/11658
DOI
10.14348/molcells.2020.0033
Publisher
한국분자세포생물학회
Related Researcher
  • Author Moon, Cheil Laboratory of Chemical Senses
  • Research Interests Brain convergent science based on chemical senses; olfaction; 감각신경계 기반 뇌융합과학; 후각 신경계
Files:
Collection:
Department of Brain and Cognitive SciencesLaboratory of Chemical Senses1. Journal Articles


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