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DC Field Value Language Son, Chang-Sik - Jin, Sang-Hyeon - Kang, Won-Seok - 2022-11-17T12:10:11Z - 2022-11-17T12:10:11Z - 2022-02-28 - 2022-02 -
dc.identifier.issn 2076-393X -
dc.identifier.uri -
dc.description.abstract This study aimed to observe adverse events following immunisation (AEFIs) that affected recovery within two weeks after COVID-19 vaccination and investigate their risks in propensityscore-matched populations. Data were collected from 447,346 reports from the VAERS between 1 January 2021 and 31 July 2021. Propensity-score-matched populations were constructed by adjusting for demographic characteristics and 11 underlying diseases in eligible subjects who received 1 of 3 COVID-19 vaccines: 19,462 Ad26.COV2.S, 120,580 mRNA-1273, and 100,752 BNT162b2. We observed that 88 suspected AEFIs (22 in Ad26.COV2.S, 62 in mRNA-1273, and 54 in BNT162b2) were associated with an increased risk of delayed recovery within 2 weeks after COVID-19 vaccinations. Nervous system, musculoskeletal and connective tissue, gastrointestinal, skin, and subcutaneous tissue disorders were the most common AEFIs after COVID-19 vaccination. Interestingly, four local and systemic reactions affected recovery in different vaccine recipients during our study period: asthenic conditions and febrile disorders in Ad26.COV2.S and mRNA-1273; general signs and symptoms in mRNA-1273 and BNT162b2; injection site reactions in Ad26.COV2.S and BNT162b2. Although it is necessary to confirm a causal relationship with COVID-19 vaccinations, some symptoms, including paralysis, allergic disorders, breathing abnormalities, and visual impairment, may hinder the recovery of these recipients. © 2022 by the authors. Licensee MDPI, Basel, Switzerland. -
dc.language English -
dc.publisher Multidisciplinary Digital Publishing Institute (MDPI) -
dc.title Propensity-Score-Matched Evaluation of Adverse Events Affecting Recovery after COVID-19 Vaccination: On Adenovirus and mRNA Vaccines -
dc.type Article -
dc.identifier.doi 10.3390/vaccines10020284 -
dc.identifier.scopusid 2-s2.0-85124831139 -
dc.identifier.bibliographicCitation Vaccines, v.10, no.2 -
dc.description.isOpenAccess TRUE -
dc.subject.keywordAuthor COVID-19 vaccine -
dc.subject.keywordAuthor adenovirus vector -
dc.subject.keywordAuthor mRNA -
dc.subject.keywordAuthor VAERS -
dc.subject.keywordAuthor adverse event -
dc.subject.keywordAuthor propensity score matching -
dc.subject.keywordPlus HEART-FAILURE -
dc.subject.keywordPlus CARE -
dc.subject.keywordPlus RISK -
dc.citation.number 2 -
dc.citation.title Vaccines -
dc.citation.volume 10 -
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Division of Intelligent Robotics 1. Journal Articles


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