Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Son, Chang-Sik | - |
dc.contributor.author | Jin, Sang-Hyeon | - |
dc.contributor.author | Kang, Won-Seok | - |
dc.date.accessioned | 2022-11-17T12:10:11Z | - |
dc.date.available | 2022-11-17T12:10:11Z | - |
dc.date.created | 2022-02-28 | - |
dc.date.issued | 2022-02 | - |
dc.identifier.issn | 2076-393X | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/17177 | - |
dc.description.abstract | This study aimed to observe adverse events following immunisation (AEFIs) that affected recovery within two weeks after COVID-19 vaccination and investigate their risks in propensityscore-matched populations. Data were collected from 447,346 reports from the VAERS between 1 January 2021 and 31 July 2021. Propensity-score-matched populations were constructed by adjusting for demographic characteristics and 11 underlying diseases in eligible subjects who received 1 of 3 COVID-19 vaccines: 19,462 Ad26.COV2.S, 120,580 mRNA-1273, and 100,752 BNT162b2. We observed that 88 suspected AEFIs (22 in Ad26.COV2.S, 62 in mRNA-1273, and 54 in BNT162b2) were associated with an increased risk of delayed recovery within 2 weeks after COVID-19 vaccinations. Nervous system, musculoskeletal and connective tissue, gastrointestinal, skin, and subcutaneous tissue disorders were the most common AEFIs after COVID-19 vaccination. Interestingly, four local and systemic reactions affected recovery in different vaccine recipients during our study period: asthenic conditions and febrile disorders in Ad26.COV2.S and mRNA-1273; general signs and symptoms in mRNA-1273 and BNT162b2; injection site reactions in Ad26.COV2.S and BNT162b2. Although it is necessary to confirm a causal relationship with COVID-19 vaccinations, some symptoms, including paralysis, allergic disorders, breathing abnormalities, and visual impairment, may hinder the recovery of these recipients. © 2022 by the authors. Licensee MDPI, Basel, Switzerland. | - |
dc.language | English | - |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | - |
dc.title | Propensity-Score-Matched Evaluation of Adverse Events Affecting Recovery after COVID-19 Vaccination: On Adenovirus and mRNA Vaccines | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/vaccines10020284 | - |
dc.identifier.scopusid | 2-s2.0-85124831139 | - |
dc.identifier.bibliographicCitation | Vaccines, v.10, no.2 | - |
dc.description.isOpenAccess | TRUE | - |
dc.subject.keywordAuthor | COVID-19 vaccine | - |
dc.subject.keywordAuthor | adenovirus vector | - |
dc.subject.keywordAuthor | mRNA | - |
dc.subject.keywordAuthor | VAERS | - |
dc.subject.keywordAuthor | adverse event | - |
dc.subject.keywordAuthor | propensity score matching | - |
dc.subject.keywordPlus | HEART-FAILURE | - |
dc.subject.keywordPlus | CARE | - |
dc.subject.keywordPlus | RISK | - |
dc.citation.number | 2 | - |
dc.citation.title | Vaccines | - |
dc.citation.volume | 10 | - |
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