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Near-field acoustic microbead trapping as remote anchor for single particle manipulation

Near-field acoustic microbead trapping as remote anchor for single particle manipulation
Hwang, J.Y.[Hwang, Jae Youn]Cheon, D.Y.[Cheon, Dong Young]Shin, H.[Shin, Hyun June]Kim, H.B.[Kim, Hyun Bin]Lee, J.[Lee, Jung Woo]
DGIST Authors
Hwang, J.Y.[Hwang, Jae Youn]
Issued Date
Article Type
Cellular ReactionsDiscrete FrequenciesDriving FrequenciesExperimental ValidationsFocused UltrasoundMaximum DisplacementMechanical DisturbanceMobile SecurityNear-Field AcousticsPolystyrenesTransducersUltrasonic Applications
We recently proposed an analytical model of a two-dimensional acoustic trapping of polystyrene beads in the ray acoustics regime, where a bead diameter is larger than the wavelength used. As its experimental validation, this paper demonstrates the transverse (or lateral) trapping of individual polystyrene beads in the near field of focused ultrasound. A 100 μm bead is immobilized on the central beam axis by a focused sound beam from a 30 MHz single element lithium niobate transducer, after being laterally displaced through hundreds of micrometers. Maximum displacement, a longest lateral distance at which a trapped bead can be directed towards the central axis, is thus measured over a discrete frequency range from 24 MHz to 36 MHz. The displacement data are found to be between 323.7 μm and 470.2 μm, depending on the transducer's driving frequency and input voltage amplitude. The experimental results are compared with their corresponding model values, and their relative errors lie between 0.9% and 3.9%. The results suggest that this remote maneuvering technique may be employed to manipulate individual cells through solid microbeads, provoking certain cellular reactions to localized mechanical disturbance without direct contact. © 2015 AIP Publishing LLC.
American Institute of Physics Inc.
Related Researcher
  • 황재윤 Hwang, Jae Youn 전기전자컴퓨터공학과
  • Research Interests Multimodal Imaging; High-Frequency Ultrasound Microbeam; Ultrasound Imaging and Analysis; 스마트 헬스케어; Biomedical optical system
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Department of Electrical Engineering and Computer Science MBIS(Multimodal Biomedical Imaging and System) Laboratory 1. Journal Articles


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