Major depressive disorder (MDD) is the most prevalent mental illness and affects up to 20 % of the population worldwide. It is a chronic, recurrent, and even life-threatening mental disease. It is one of the major causes of morbidity and mortality, and it has become an increasingly greater health, social and economic burden. Still, current therapeutics has been largely limited to treat this disease timely and effectively without unnecessary side effects. Despite intense research over several decades, our understanding of the pathophysiology of this disease, as well as the anti-depressive mechanism of the current therapeutics, has remained elusive.
Advisor Professor : Oh, Yong Seok Laboratory of Neural Signaling Networks Homepage