Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 오용석 | - |
| dc.contributor.author | Mina Kang | - |
| dc.date.accessioned | 2023-09-18T21:00:56Z | - |
| dc.date.available | 2024-08-31T06:00:29Z | - |
| dc.date.issued | 2023 | - |
| dc.identifier.uri | http://hdl.handle.net/20.500.11750/46419 | - |
| dc.identifier.uri | http://dgist.dcollection.net/common/orgView/200000686982 | - |
| dc.description | Early life stress; Cognitive; Hippocampus; Mossy cell; Pattern separation; Context discrimination | - |
| dc.description.tableofcontents | Abstract i List of contents ii Ⅰ. Introduction 1 ⅠⅠ. Method 5 2.1 Animal 5 2.2 Early life stress 5 2.3 Behavior test 5 2.3.1 Open field test 6 2.3.2 Light dark box 6 2.3.3 Elevated plus maze 6 2.3.4 Novelty suppressed feeding 6 2.3.5 Tail suspension test 7 2.3.6 Pattern separation 7 2.4 Stereotaxic surgery 8 2.5 Immunohistochemistry 8 2.6 Fluorescence imaging 9 2.7 Statistics 9 ⅠⅠⅠ. Result 10 3.1 Early life stress model with limited bedding and behavior validation. 10 3.2 ELS affects mild anxiety-like behavior, particularly LD box test in adults. 10 3.3 ELS had no effect on the number of MCs. 11 3.4 ELS had no effect on the exonal projection pattern of MCs. 11 3.5 ELS suppresses the expression of the MCs neurotransmitter, GluR2/3. 12 3.6 ELS reduced the cell activity of MCs and GCs. 12 3.7 ELS impaired rapid context discrimination. 13 IV. Graphical Summary 31 V. Discussion 32 VI. References 35 VII. Summary in Korean 40 |
- |
| dc.format.extent | 40 | - |
| dc.language | eng | - |
| dc.publisher | DGIST | - |
| dc.title | Dysregulation of mossy cell by early life stress and its implication in cognitive deficit in adults | - |
| dc.type | Thesis | - |
| dc.identifier.doi | 10.22677/THESIS.200000686982 | - |
| dc.description.degree | Master | - |
| dc.contributor.department | Department of Brain Sciences | - |
| dc.contributor.coadvisor | Hyosang Lee | - |
| dc.date.awarded | 2023-08-01 | - |
| dc.publisher.location | Daegu | - |
| dc.description.database | dCollection | - |
| dc.citation | XT.BM 강38 202308 | - |
| dc.date.accepted | 2023-09-14 | - |
| dc.contributor.alternativeDepartment | 뇌과학과 | - |
| dc.subject.keyword | Early life stress | - |
| dc.subject.keyword | Cognitive | - |
| dc.subject.keyword | Hippocampus | - |
| dc.subject.keyword | Mossy cell | - |
| dc.subject.keyword | Pattern separation | - |
| dc.subject.keyword | Context discrimination | - |
| dc.contributor.affiliatedAuthor | Mina Kang | - |
| dc.contributor.affiliatedAuthor | Yong-Seok Oh | - |
| dc.contributor.affiliatedAuthor | Hyosang Lee | - |
| dc.contributor.alternativeName | 강민아 | - |
| dc.contributor.alternativeName | Yong-Seok Oh | - |
| dc.contributor.alternativeName | 이효상 | - |
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