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This paper presents compact single-ended wireline transceivers with software-generated receiver front-ends. The developed software framework significantly shortens the physical design time of 1/N-rate wireline receiver front-ends. The physical layouts of various receiver front-ends were software-generated in four different CMOS technology nodes (28 nm, 40 nm, 65 nm, and 90 nm) with four different front-end architectures targeting various data rates. In the post-layout simulation, the receiver front-ends generated within a second by the software achieved nearly the same performances as the manually-designed receiver front-ends that require more than about 30 hours of design time. For demonstration, we generated 8 Gb/s full-rate, 10 Gb/s half-rate, 12 Gb/s, and 20 Gb/s quarter-rate receiver front-ends, and fabricated them with a manually-designed feed-forward equalization transmitter in 28 nm CMOS process. The transceivers were measured with the data rate up to 20 Gb/s while consuming 1.39 pJ/b at the channel loss of