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Artificial Intelligence and Multi-Omics Integration for Parkinson’s Disease Drug Development

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Title
Artificial Intelligence and Multi-Omics Integration for Parkinson’s Disease Drug Development
Issued Date
2026-05
Citation
Molecules and Cells, v.49, no.5, pp.100343
Type
Article
Author Keywords
Drug discovery ; Multiomics ; Parkinson&apos ; s disease ; Artificial intelligence
Keywords
DEEP-BRAIN-STIMULATION ; ALZHEIMERS-DISEASE ; MOTOR FLUCTUATIONS ; ANIMAL-MODELS ; DOUBLE-BLIND ; LEVODOPA ; THERAPY ; DIAGNOSIS ; HEALTH ; EPIDEMIOLOGY
ISSN
1016-8478
Abstract

Recent advances underscore the potential of integrating multiomics, such as genomics, transcriptomics, proteomics, and metabolomics, and artificial intelligence to overcome limitations regarding early diagnosis and treatment of Parkinson's disease. Developing a comprehensive view of the complex molecular landscape of Parkinson's disease through artificial intelligence algorithms would enable the processing of extensive multiomics datasets. Applying these integrative technologies to Parkinson's disease research would improve early diagnosis, support personalized therapeutic strategies, and drug discovery. This review explores the transformative potential of integrating multiomics and artificial intelligence in Parkinson's disease, outlining a framework to advance diagnosis, treatment, and drug development in neurodegenerative diseases.

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URI
https://scholar.dgist.ac.kr/handle/20.500.11750/61070
DOI
10.1016/j.mocell.2026.100343
Publisher
한국분자세포생물학회
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오용석
Oh, Yong-Seok오용석

Department of Brain Sciences

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