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Fabrication and Characterization of a Magnetic Drilling Actuator for Navigation in a Three-dimensional Phantom Vascular Network

Title
Fabrication and Characterization of a Magnetic Drilling Actuator for Navigation in a Three-dimensional Phantom Vascular Network
Authors
Lee, Sun KeyLee, Seung MinKim, SangwonYoon, Chang-HwanPark, Hun-JunKim, Jin YoungChoi, Hong Soo
DGIST Authors
Kim, Jin YoungChoi, Hong Soo
Issue Date
2018-02
Citation
Scientific Reports, 8
Type
Article
Article Type
Article
Keywords
Acute Myocardial-InfarctionCoronary-Artery-DiseasePrimary AngioplastyMicrorobotsTherapyAtherosclerosisInterventionsMicromachinesAssociationMortality
ISSN
2045-2322
Abstract
Intravascular microrobots have emerged as a promising tool for vascular diseases. They can be wirelessly and precisely manipulated with a high degree of freedom. Previous studies have evaluated their drilling performance and locomotion, and showed the feasibility of using microrobots for biomedical applications in two-dimensional space. However, it is critical to validate micro-drillers in a three-dimensional (3D) environment because gravity plays an important role in a 3D environment and significantly affects the performance of the micro-drillers in vascular networks. In this work, we fabricated magnetic drilling actuators (MDAs) and characterized their locomotion and drilling performance in vascular network-mimicking fluidic channels. The MDAs were precisely manipulated in the fluidic channel network in both horizontal and vertical planes, selecting and moving through the desired path via the junctions of multiple channels. The MDAs also accurately navigated an artificial thrombosis in an artificial 3D vascular network and successfully drilled through it. The results obtained here confirmed the precise manipulation and drilling performance of the developed MDAs in 3D. We think that the MDAs presented in this paper have great potential as intravascular drillers for precise thrombus treatment. © 2018 The Author(s).
URI
http://hdl.handle.net/20.500.11750/6160
DOI
10.1038/s41598-018-22110-5
Publisher
NATURE PUBLISHING GROUP
Related Researcher
  • Author Choi, Hong Soo Bio-Micro Robotics Lab
  • Research Interests Micro/Nano robot; Neural prostheses; MEMS; BMI; MEMS/NEMS; BioMEMS; MEMS 초음파 트랜스듀스; 인공와우
Files:
Collection:
DGIST-ETH Microrobotics Research Center1. Journal Articles
Department of Robotics EngineeringBio-Micro Robotics Lab1. Journal Articles


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