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ArmA and RmtB Were the Predominant 16S RMTase Genes Responsible for Aminoglycoside-resistant Isolates in Korea

Title
ArmA and RmtB Were the Predominant 16S RMTase Genes Responsible for Aminoglycoside-resistant Isolates in Korea
Authors
Lee, Tae HeeHwang, Joo-HeeLee, Woo KonShin, Min-KyoungWoo, Hye RyunChung, Kyung MinLee, Chang-Seop
DGIST Authors
Woo, Hye Ryun
Issue Date
2018-10
Citation
Journal of Korean Medical Science, 33(42), 1-5
Type
Article
Article Type
Article
Author Keywords
Aminoglycoside ResistanceArmARmtBKorea
Keywords
RIBOSOMAL-RNA METHYLASESPECTRUM BETA-LACTAMASEKLEBSIELLA-PNEUMONIAEESCHERICHIA-COLIACINETOBACTER-BAUMANNIISOUTH-KOREAMETHYLTRANSFERASEAMIKACINENTEROBACTERIACEAEDISSEMINATION
ISSN
1011-8934
Abstract
Pathogenic gram-negatives that produce 16S ribosomal RNA methyltransferases (16S RMTases) have already been distributed all over the world. To investigate the predominance of aminoglycoside resistance associated with 16S RMTases in Korea, we collected a total of 222 amikacin resistant Gram-negative clinical isolates from patient specimens between 1999 and 2015 from three hospital banks across Korea. ArmA and nntB were the predominant 16S RMTase genes responsible for aminoglycoside-resistant isolates circulating in Korean community settings although only one rmtA-producing isolate was detected in 2006.
URI
http://hdl.handle.net/20.500.11750/9374
DOI
10.3346/jkms.2018.33.e262
Publisher
대한의학회
Related Researcher
  • Author Woo, Hye Ryun Lab of Plant Molecular Communication
  • Research Interests Genome biology; Epigenomics; Plant senescence
Files:
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Collection:
Department of New BiologyCBRG(Complex Biology Research Group)1. Journal Articles


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