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Showing results 1 to 38 of 38
- Nam, Youngpyo ;
- Joo, Bitna ;
- Lee, Ju-Young ;
- Han, Kyung-Min ;
- Ryu, Ka-Young ;
- Koh, Young Ho ;
- Kim, Jeongyeon ;
- Koo, Ja Wook ;
- We, Young-Man ;
- Hoe, Hyang-Sook
- 2019-08
- Nam, Youngpyo. (2019-08). ALWPs Improve Cognitive Function and Regulate A beta Plaque and Tau Hyperphosphorylation in a Mouse Model of Alzheimer's Disease. doi: 10.3389/fnmol.2019.00192
- Frontiers Media S.A.
- View : 729
- Download : 116
- Lee, Ju-Young ;
- 주빛나 ;
- Nam, Jin Han ;
- Nam, Hye Yeon ;
- Lee, Wonil ;
- Nam, Youngpyo ;
- Seo, Yongtaek ;
- Kang, Hye-Jin ;
- Cho, Hyun-Ji ;
- Jang, Young Pyo ; et al
- 2018-09
- Lee, Ju-Young. (2018-09). An Aqueous Extract of Herbal Medicine ALWPs Enhances Cognitive Performance and Inhibits LPS-Induced Neuroinflammation via FAK/NF-kappa B Signaling Pathways. doi: 10.3389/fnagi.2018.00269
- Frontiers Media S.A.
- View : 742
- Download : 128
- Park, Hyun Ha ;
- Kim, Byeong-Hyeon ;
- Leem, Seol Hwa ;
- Park, Yong Ho ;
- ;
- Nam, Yunkwon ;
- Kim, Sujin ;
- Shin, Soo Jung ;
- Moon, Minho
- 2023-09
- Park, Hyun Ha. (2023-09). Characterization of age- and stage-dependent impaired adult subventricular neurogenesis in 5XFAD mouse model of Alzheimer’s disease. BMB Reports, 56(9), 520–525. doi: 10.5483/BMBRep.2023-0071
- The Biochemical Society of the Republic of Korea
- View : 185
- Download : 41
- Lee, Hyun-ju ;
- Kang, Sora ;
- ;
- Park, Jin-Hee ;
- Hwang, Jeong-Woo ;
- Gu, Chan-Hu ;
- Jung, Tae-Mi ;
- Oh, Seokjun ;
- ;
- 2025-07
- Molecular Brain, v.18, no.1
- BioMed Central
- View : 995
- Download : 0
- Lee, Hyun-ju ;
- ;
- Kim, Jun-Su ;
- Kim, Seung-Jae ;
- Jo, Unhui ;
- Jun, Su Jin ;
- Lim, Jongmin ;
- Park, Jin-Yeop ;
- Lee, Myungji ;
- Kim, Donggi ; et al
- 2025-06
- Lee, Hyun-ju. (2025-06). Current Status and Future Directions in the Development of Digital Therapeutic Interventions for Neurodevelopmental Disorders. Clinical Pharmacology and Therapeutics, 117(6), 1632–1636. doi: 10.1002/cpt.3633
- Wiley
- View : 91
- Download : 0
- Ryu, Ka-Young ;
- Lee, Hyun-Ju ;
- Woo, Hanwoong ;
- Kang, Ri-Jin ;
- Han, Kyung-Min ;
- Park, HyunHee ;
- Lee, Sang Min ;
- Lee, Ju-Young ;
- Jeong, Yoo Joo ;
- Nam, Hyun-Wook ; et al
- 2019-10
- Ryu, Ka-Young. (2019-10). Dasatinib regulates LPS-induced microglial and astrocytic neuroinflammatory responses by inhibiting AKT/STAT3 signaling. doi: 10.1186/s12974-019-1561-x
- BioMed Central
- View : 766
- Download : 147
- Lee, Hyun-ju ;
- Choi, Hee-Jeong ;
- ;
- Na, Yoon-Hee ;
- Hong, Jin Tae ;
- Han, Ji Min ;
- ;
- Lim, Key-Hwan
- 2024-06
- Lee, Hyun-ju. (2024-06). Developing theragnostics for Alzheimer's disease: Insights from cancer treatment. International Journal of Biological Macromolecules, 269. doi: 10.1016/j.ijbiomac.2024.131925
- Elsevier
- View : 179
- Download : 77
- ;
- Lee, Hyun-ju ;
- Kim, Jun-Su ;
- Kim, Seung-Jae ;
- Jo, Unhui ;
- Park, Jin Yeop ;
- Jun, Su Jin ;
- Lee, Won Seok ;
- Song, Mingoo ;
- Kim, Donggii ; et al
- 2026-01
- Medicinal Research Reviews, v.46, no.1, pp.316 - 327
- Wiley
- View : 99
- Download : 0
- Kim, Jieun ;
- Lee, Hyun-ju ;
- Park, Seon Kyeong ;
- Park, Jin-Hee ;
- Jeong, Ha-Ram ;
- Lee, Soojung ;
- Lee, Heeyong ;
- Seol, Eunyoung ;
- Hoe, Hyang-Sook
- 2021-10
- Kim, Jieun. (2021-10). Donepezil Regulates LPS and Aβ-Stimulated Neuroinflammation through MAPK/NLRP3 Inflammasome/STAT3 Signaling. doi: 10.3390/ijms221910637
- Multidisciplinary Digital Publishing Institute (MDPI)
- View : 446
- Download : 105
- Choi, Hee-Jeong ;
- ;
- Kim, Jieun ;
- 2023-08
- Choi, Hee-Jeong. (2023-08). EGFR is a potential dual molecular target for cancer and Alzheimer’s disease. Frontiers in Pharmacology, 14. doi: 10.3389/fphar.2023.1238639
- Frontiers
- View : 207
- Download : 22
- Jeon, Min-Tae ;
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- Lee, Suji ;
- Kim, Jieun ;
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- Kim, Do-Geun
- 2021-07
- Jeon, Min-Tae. (2021-07). Emerging pathogenic role of peripheral blood factors following BBB disruption in neurodegenerative disease. Ageing Research Reviews, 68, 101333. doi: 10.1016/j.arr.2021.101333
- Elsevier BV
- View : 524
- Download : 0
Article
Erdafitinib diminishes LPS-mediated neuroinflammatory responses through NLRP3 in wild-type mice
- Lee, Hyun-ju ;
- Kim, Se Ha ;
- Jung, Tae-Mi ;
- Kim, Yu-Jin ;
- Gu, Chan-Hu ;
- ;
- Song, Jeong-Heon ;
- 2025-06
- Frontiers in Pharmacology, v.16
- Frontiers Media
- View : 1048
- Download : 10
Article
Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD
- Lee, Hyun-Ju ;
- Hwang, Jeong-Woo ;
- Kim, Jieun ;
- Jo, A-Ran ;
- Park, Jin-Hee ;
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- Kim, Su-Jeong ;
- Song, Jeong-Heon ;
- 2024-10
- Lee, Hyun-Ju. (2024-10). Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD. Frontiers in Immunology, 15. doi: 10.3389/fimmu.2024.1421455
- Frontiers Media
- View : 220
- Download : 24
- Hwang, Jeong-Woo ;
- Kim, Jeongha ;
- Park, Jin-Hee ;
- Nam, Jinhan ;
- ;
- Jo, Aran ;
- Lee, Hyun-Ju ;
- 2024-09
- Hwang, Jeong-Woo. (2024-09). Felodipine attenuates neuroinflammatory responses and tau hyperphosphorylation through JNK/P38 signaling in tau-overexpressing AD mice. Molecular Brain, 17(1). doi: 10.1186/s13041-024-01137-y
- BioMed Central
- View : 289
- Download : 35
- Kim, Jieun ;
- Han, Jung-Youn ;
- Lee, Yujeong ;
- Kim, Kipom ;
- Choi, Young Pyo ;
- Chae, Sehyun ;
- 2023-01
- Kim, Jieun. (2023-01). Genetic deletion of nitric oxide synthase 2 ameliorates Parkinson’s disease pathology and neuroinflammation in a transgenic mouse model of synucleinopathy. Molecular Brain, 16(1). doi: 10.1186/s13041-023-00996-1
- BioMed Central
- View : 194
- Download : 0
- Lee, Hyun-ju ;
- Jeon, Seong Gak ;
- Kim, Jieun ;
- Kang, Ri Jin ;
- Kim, Seong-Min ;
- Han, Kyung-Min ;
- Park, HyunHee ;
- Kim, Ki-taek ;
- Sung, You Me ;
- Nam, Hye Yeon ; et al
- 2021-03
- Lee, Hyun-ju. (2021-03). Ibrutinib modulates Aβ/tau pathology, neuroinflammation, and cognitive function in mouse models of Alzheimer's disease. Aging Cell, 20(3), e13332. doi: 10.1111/acel.13332
- Blackwell Publishing Inc.
- View : 513
- Download : 0
- Lee, Hyun-ju ;
- Jeong, Ha-Ram ;
- Park, Jin-Hee ;
- 2021-09
- Lee, Hyun-ju. (2021-09). Idebenone Decreases Aβ Pathology by Modulating RAGE/Caspase-3 Signaling and the Aβ Degradation Enzyme NEP in a Mouse Model of AD. Biology, 10(9). doi: 10.3390/biology10090938
- MDPI
- View : 487
- Download : 76
- Lee, Hyun-ju ;
- Park, Jin-Hee ;
- 2022-02
- Lee, Hyun-ju. (2022-02). Idebenone Regulates A beta and LPS-Induced Neurogliosis and Cognitive Function Through Inhibition of NLRP3 Inflammasome/IL-1 beta Axis Activation. Frontiers in Immunology, 13. doi: 10.3389/fimmu.2022.749336
- Frontiers Media S.A.
- View : 320
- Download : 0
- Lee, Hyun-ju ;
- Choi, Tae-Ik ;
- Kim, Yong-Min ;
- Lee, Soonje ;
- Han, Bing ;
- Bak, In Seon ;
- ;
- Yu, Dae-Yeul ;
- Shin, Ki Soon ;
- Kwon, Yunhee Kim ; et al
- 2021-08
- Lee, Hyun-ju. (2021-08). Identification of Gng8-expressing cell types in the MHb and IPN. Molecular Psychiatry, 26(8), 3665–3665. doi: 10.1038/s41380-021-01278-9
- Nature Publishing Group
- View : 609
- Download : 0
- Lee, Hyun-ju ;
- 2023-04
- Lee, Hyun-ju. (2023-04). Inhibition of CDK4/6 regulates AD pathology, neuroinflammation and cognitive function through DYRK1A/STAT3 signaling. Pharmacological Research, 190. doi: 10.1016/j.phrs.2023.106725
- Academic Press
- View : 190
- Download : 87
- Kim, Sujin ;
- Shin, Soo Jung ;
- Nam, Yunkwon ;
- Park, Yong Ho ;
- Kim, Byeong-Hyeon ;
- Park, Hyun Ha ;
- Kumar, Vijay ;
- Yoo, Doo-Han ;
- Lee, Yong Yook ;
- ; et al
- 2024-04
- Kim, Sujin. (2024-04). Korean red ginseng polysaccharide as a potential therapeutic agent targeting tau pathology in Alzheimer's disease. International Journal of Biological Macromolecules, 263. doi: 10.1016/j.ijbiomac.2024.130516
- Elsevier
- View : 164
- Download : 0
Article
L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD
- Lee, Hyun-ju ;
- Nam, Jinhan ;
- Hwang, Jeong-Woo ;
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- ;
- Kim, Su-Jeong ;
- Jo, A-Ran ;
- 2024-04
- Lee, Hyun-ju. (2024-04). L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD. Molecular Brain, 17(1). doi: 10.1186/s13041-024-01092-8
- BioMed Central
- View : 104
- Download : 35
- Kim, Jieun ;
- Jeon, Seong Gak ;
- Jeong, Ha-Ram ;
- Park, HyunHee ;
- Kim, Jae-Ick ;
- 2022-11
- Kim, Jieun. (2022-11). L-Type Ca2+ Channel Inhibition Rescues the LPS-Induced Neuroinflammatory Response and Impairments in Spatial Memory and Dendritic Spine Formation. International Journal of Molecular Sciences, 23(21). doi: 10.3390/ijms232113606
- MDPI
- View : 355
- Download : 0
- ;
- Hwang, Jeong-Woo ;
- Lee, Hyun-ju ;
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- ;
- Seo, Jinsoo ;
- 2023-06
- Park, Jin-Hee. (2023-06). Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β. Frontiers in Immunology, 14. doi: 10.3389/fimmu.2023.1150940
- Frontiers Media
- View : 276
- Download : 27
- Nam, Yunkwon ;
- Kim, Sujin ;
- Kim, Jieun ;
- ;
- Moon, Minho
- 2022-12
- Nam, Yunkwon. (2022-12). Mesoscopic Mapping of Visual Pathway in a Female 5XFAD Mouse Model of Alzheimer’s Disease. Cells, 11(23). doi: 10.3390/cells11233901
- MDPI
- View : 165
- Download : 0
- Han, Kyeong-Min
- 2020
- Han, Kyeong-Min. (2020). Multi target kinase inhibitor X regulates AD pathology, neuroinflammation, as well as dendritic spinogenesis. doi: 10.22677/thesis.200000322086
- DGIST
- View : 535
- Download : 0
- Moon, Dae Won ;
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- ;
- Kwak, SuHwa ;
- Kim, Minseok S. ;
- Kim, Hyunmin ;
- Kim, Eunjoo ;
- Jung, Yebin ;
- Hoe, Hyang-Sook ; et al
- 2020-04
- Moon, Dae Won. (2020-04). Multiplex Protein Imaging with Secondary Ion Mass Spectrometry Using Metal Oxide Nanoparticle-Conjugated Antibodies. ACS Applied Materials & Interfaces, 12(15), 18056–18064. doi: 10.1021/acsami.9b21800
- American Chemical Society
- View : 963
- Download : 0
- Kim, Jieun ;
- Lee, Hyun-ju ;
- ;
- Cha, Byung-Yoon ;
- 2022-07
- Kim, Jieun. (2022-07). Nilotinib modulates LPS-induced cognitive impairment and neuroinflammatory responses by regulating P38/STAT3 signaling. Journal of Neuroinflammation, 19(1). doi: 10.1186/s12974-022-02549-0
- BioMed Central
- View : 335
- Download : 0
- Lee, Hyun-ju ;
- Hwang, Jeong-Woo ;
- ;
- ;
- Jang, Ji-Yeong ;
- 2023-08
- Lee, Hyun-ju. (2023-08). Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD. Molecular Brain, 16(1). doi: 10.1186/s13041-023-01051-9
- BioMed Central
- View : 130
- Download : 0
- Lee, Hyun-ju ;
- ;
- Trotter, Justin H. ;
- Maher, James N. ;
- Keenoy, Kathleen E. ;
- Jang, You Mi ;
- Lee, Youngeun ;
- Kim, Jae-Ick ;
- Weeber, Edwin J. ;
- 2023-02
- Lee, Hyun-ju. (2023-02). Reelin and APP Cooperatively Modulate Dendritic Spine Formation In Vitro and In Vivo. Experimental Neurobiology, 32(1), 42–55. doi: 10.5607/en22044
- 한국뇌신경과학회
- View : 344
- Download : 0
- Han, Kyung-Min ;
- Kang, Ri Jin ;
- Jeon, Hyongjun ;
- Lee, Hyun-ju ;
- Lee, Ji-Soo ;
- Park, HyunHee ;
- Jeon, Seong Gak ;
- Suk, Kyoungho ;
- Seo, Jinsoo ;
- Hoe, Hyang-Sook
- 2020-07
- Han, Kyung-Min. (2020-07). Regorafenib Regulates AD Pathology, Neuroinflammation, and Dendritic Spinogenesis in Cells and a Mouse Model of AD. doi: 10.3390/cells9071655
- MDPI AG
- View : 663
- Download : 212
- Lee, Hyun-ju ;
- Choi, Tae-Ik ;
- Kim, Yong-Min ;
- Lee, Soonje ;
- Han, Bing ;
- Bak, In Seon ;
- ;
- Yu, Dae-Yeul ;
- Shin, Ki Soon ;
- Kim Kwon, Yunhee ; et al
- 2021-08
- Lee, Hyun-ju. (2021-08). Regulation of habenular G-protein gamma 8 on learning and memory via modulation of the central acetylcholine system. Molecular Psychiatry, 26(8), 3737–3750. doi: 10.1038/s41380-020-00893-2
- Nature Publishing Group
- View : 763
- Download : 0
- Lee, Hyun-ju ;
- 2023-10
- Lee, Hyun-ju. (2023-10). Repurposing ibrutinib: therapeutic effects and implications for translational approaches in Alzheimer's disease. Neural Regeneration Research, 18(10), 2194–2195. doi: 10.4103/1673-5374.369108
- Neural Regeneration Research
- View : 80
- Download : 34
- Kim, Jieun ;
- Park, Jin-Hee ;
- Park, Seon Kyeong ;
- Hoe, Hyang-Sook
- 2021-05
- Kim, Jieun. (2021-05). Sorafenib Modulates the LPS- and A beta-Induced Neuroinflammatory Response in Cells, Wild-Type Mice, and 5xFAD Mice. doi: 10.3389/fimmu.2021.684344
- Frontiers Media S.A.
- View : 526
- Download : 143
- Kim, Jieun ;
- Park, Jin-Hee ;
- Shah, Keshvi ;
- Mitchell, Scott John ;
- Cho, Kwangwook ;
- 2021-10
- Kim, Jieun. (2021-10). The Anti-diabetic Drug Gliquidone Modulates Lipopolysaccharide-Mediated Microglial Neuroinflammatory Responses by Inhibiting the NLRP3 Inflammasome. Frontiers in Aging Neuroscience, 13. doi: 10.3389/fnagi.2021.754123
- Frontiers Media S.A.
- View : 330
- Download : 127
- Chae, Sehyun ;
- Lee, Hyun-ju ;
- Lee, Ha-Eun ;
- Kim, Jieun ;
- ;
- Lin, Yuxi ;
- Kim, Hye Yun ;
- Leriche, Geoffray ;
- Ehrlich, Rachel S. ;
- Lingl, Sascha Castro ; et al
- 2024-08
- Chae, Sehyun. (2024-08). The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta. Journal of Neuroinflammation, 21(1). doi: 10.1186/s12974-024-03180-x
- BioMed Central
- View : 254
- Download : 37
- Park, HyunHee ;
- Han, Kyung-Min ;
- Jeon, Hyongjun ;
- Lee, Ji-Soo ;
- Lee, Hyunju ;
- Jeon, Seong Gak ;
- Park, Jin-Hee ;
- Kim, Yu Gyung ;
- Lin, Yuxi ;
- Lee, Young-Ho ; et al
- 2020-09
- Park, HyunHee. (2020-09). The MAO Inhibitor Tranylcypromine Alters LPS- and A beta-Mediated Neuroinflammatory Responses in Wild-type Mice and a Mouse Model of AD. doi: 10.3390/cells9091982
- NLM (Medline)
- View : 607
- Download : 102
- Lee, Hyun-ju ;
- Woo, Hanwoong ;
- Lee, Ha-Eun ;
- Jeon, Hyongjun ;
- Ryu, Ka-Young ;
- Nam, Jin han ;
- Jeon, Seong Gak ;
- Park, HyunHee ;
- Lee, Ji-Soo ;
- Han, Kyung-Min ; et al
- 2020-11
- Lee, Hyun-ju. (2020-11). The novel DYRK1A inhibitor KVN93 regulates cognitive function, amyloid-beta pathology, and neuroinflammation. doi: 10.1016/j.freeradbiomed.2020.08.030
- Elsevier Inc.
- View : 577
- Download : 0
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