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Showing results 1 to 16 of 16

Article
A crucial role of ROCK for alleviation of senescence-associated phenotype
  • Park, J.T. ; 
  • Kang, H.T. ; 
  • Park, C.H. ; 
  • Lee, Young Sam ; 
  • Cho, K.A. ; 
  • Park, Sang Chul
  • 2018-06
  • Park, J.T. (2018-06). A crucial role of ROCK for alleviation of senescence-associated phenotype. doi: 10.1016/j.exger.2018.02.012
  • Elsevier BV
  • View : 984
  • Download : 0

An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons

Article
An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons
  • Boselli, Monica ; 
  • Lee, Byung Hoon ; 
  • Robert, Jessica ; 
  • Prado, Miguel A. ; 
  • Min, Sang-Won ; 
  • Cheng, Chialin ; 
  • Silva, M. Catarina ; 
  • Seong, Changhyun ; 
  • Elsasser, Suzanne ; 
  • Hatle, Ketki M. ; 
    • et al
  • 2017-11
  • Journal of Biological Chemistry, v.292, no.47, pp.19209 - 19225
  • AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
  • View : 934
  • Download : 167

Biallelic USP14 variants cause a syndromic neurodevelopmental disorder

Article
Biallelic USP14 variants cause a syndromic neurodevelopmental disorder
  • Ebstein, Frédéric ; 
  • Latypova, Xenia ; 
  • Sharon Hung, Ka Ying ; 
  • Prado, Miguel A. ; 
  • Lee, Byung-Hoon ; 
  • Möller, Sophie ; 
  • Wendlandt, Martin ; 
  • Zieba, Barbara A. ; 
  • Florenceau, Laëtitia ; 
  • Vignard, Virginie ; 
    • et al
  • 2024-06
  • Ebstein, Frédéric. (2024-06). Biallelic USP14 variants cause a syndromic neurodevelopmental disorder. Genetics in Medicine, 26(6). doi: 10.1016/j.gim.2024.101120
  • Elsevier
  • View : 427
  • Download : 61

Chronic restraint stress induces hippocampal memory deficits by impairing insulin signaling

Article
Chronic restraint stress induces hippocampal memory deficits by impairing insulin signaling
  • Woo, Han Woong ; 
  • Hong, Caroline Jeeyeon ; 
  • Jung, Seong Hee ; 
  • Choe, Seong Won ; 
  • Yu, Seong-Woon
  • 2018-07
  • Woo, Han Woong. (2018-07). Chronic restraint stress induces hippocampal memory deficits by impairing insulin signaling. doi: 10.1186/s13041-018-0381-8
  • BioMed Central Ltd.
  • View : 904
  • Download : 134

Iron accumulation and changes in cellular organelles in wdr45 mutant fibroblasts

Article
Iron accumulation and changes in cellular organelles in wdr45 mutant fibroblasts
  • Lee, Hye Eun ; 
  • Jung, Min Kyo ; 
  • Noh, Seul Gi ; 
  • Choi, Hye Bin ; 
  • Chae, Se Hyun ; 
  • Lee, Jae Hyeok ; 
  • Mun, Ji Young
  • 2021-11
  • Lee, Hye Eun. (2021-11). Iron accumulation and changes in cellular organelles in wdr45 mutant fibroblasts. doi: 10.3390/ijms222111650
  • MDPI
  • View : 426
  • Download : 75

Lithium and exercise ameliorate insulin-deficient hyperglycemia by independently attenuating pancreatic α-cell mass and hepatic gluconeogenesis

Article
Lithium and exercise ameliorate insulin-deficient hyperglycemia by independently attenuating pancreatic α-cell mass and hepatic gluconeogenesis
  • Jung, Su-Ryun ; 
  • Lee, Ji-Hye ; 
  • Ryu, Hanguk ; 
  • Gao, Yurong ; 
  • Lee, Jaemin
  • 2024-01
  • Jung, Su-Ryun. (2024-01). Lithium and exercise ameliorate insulin-deficient hyperglycemia by independently attenuating pancreatic α-cell mass and hepatic gluconeogenesis. Korean Journal of Physiology & Pharmacology, 28(1), 31–38. doi: 10.4196/kjpp.2024.28.1.31
  • the Korean Physiological Society (KPS) and the Korean Society of Pharmacology (KSP)
  • View : 358
  • Download : 45
Article
Mitochondrial metabolic reprograming via BRAF inhibition ameliorates senescence
  • Kim, Jae Won ; 
  • Kuk, Myeong Uk ; 
  • Choy, Hyon E. ; 
  • Park, Sang Chul ; 
  • Park, Joon Tae
  • 2019-10
  • Kim, Jae Won. (2019-10). Mitochondrial metabolic reprograming via BRAF inhibition ameliorates senescence. doi: 10.1016/j.exger.2019.110691
  • Elsevier Inc.
  • View : 610
  • Download : 0
Article
Pharmacological inhibition of USP14 delays proteostasis-associated aging in a proteasome-dependent but foxo-independent manner
  • Lim, Jin Ju ; 
  • Noh, Sujin ; 
  • Kang, Woojun ; 
  • Hyun, Bom ; 
  • Lee, Byung-Hoon ; 
  • Hyun, Seogang
  • 2024-12
  • Lim, Jin Ju. (2024-12). Pharmacological inhibition of USP14 delays proteostasis-associated aging in a proteasome-dependent but foxo-independent manner. Autophagy, 20(12), 2752–2768. doi: 10.1080/15548627.2024.2389607
  • Taylor and Francis
  • View : 268
  • Download : 0

Primary cilia mediate mitochondrial stress responses to promote dopamine neuron survival in a Parkinson’s disease model

Article
Primary cilia mediate mitochondrial stress responses to promote dopamine neuron survival in a Parkinson’s disease model
  • Bae, Ji-Eun ; 
  • Kang, Gil Myung ; 
  • Min, Se Hee ; 
  • Jo, Doo Sin ; 
  • Jung, Yong-Keun ; 
  • Kim, Keetae ; 
  • Kim, Min-Seon ; 
  • Cho, Dong-Hyung
  • 2019-12
  • Bae, Ji-Eun. (2019-12). Primary cilia mediate mitochondrial stress responses to promote dopamine neuron survival in a Parkinson’s disease model. doi: 10.1038/s41419-019-2184-y
  • Springer Nature
  • View : 722
  • Download : 218
Article
PTK2 regulates tau-induced neurotoxicity via phosphorylation of p62 at Ser403
  • Lee, Shinrye ; 
  • Jo, Myungjin ; 
  • Kwon, Younghwi ; 
  • Jeon, Yu-Mi ; 
  • Kim, Seyeon ; 
  • Lee, Kea Joo ; 
  • Kim, Hyung-Jun
  • 2023-04
  • Lee, Shinrye. (2023-04). PTK2 regulates tau-induced neurotoxicity via phosphorylation of p62 at Ser403. Journal of Neurogenetics, 37(1–2), 10–19. doi: 10.1080/01677063.2022.2114471
  • Taylor & Francis
  • View : 372
  • Download : 0
Article
Rhein Suppresses Colorectal Cancer Cell Growth by Inhibiting the mTOR Pathway In Vitro and In Vivo
  • Zhang, Haibo ; 
  • Yi, Jun-Koo ; 
  • Huang, Hai ; 
  • Park, Song ; 
  • Park, Sijun ; 
  • Kwon, Wookbong ; 
  • Kim, Eungyung ; 
  • Jang, Soyoung ; 
  • Kim, Si-Yong ; 
  • Choi, Seong-Kyoon ; 
    • et al
  • 2021-05
  • Zhang, Haibo. (2021-05). Rhein Suppresses Colorectal Cancer Cell Growth by Inhibiting the mTOR Pathway In Vitro and In Vivo. Cancers, 13(9), 2176. doi: 10.3390/cancers13092176
  • Multidisciplinary Digital Publishing Institute (MDPI)
  • View : 325
  • Download : 0
Article
Tanycytic TSPO Inhibition Induces Lipophagy to Regulate Lipid Metabolism and Improve Energy Balance
  • 2020-07
  • Kim, Seolsong. (2020-07). Tanycytic TSPO Inhibition Induces Lipophagy to Regulate Lipid Metabolism and Improve Energy Balance. Autophagy, 16(7), 1200–1220. doi: 10.1080/15548627.2019.1659616
  • Taylor and Francis Inc.
  • View : 767
  • Download : 0

The Role of HDAC6 in TDP-43-Induced Neurotoxicity and UPS Impairment

Article
The Role of HDAC6 in TDP-43-Induced Neurotoxicity and UPS Impairment
  • Lee, Shinrye ; 
  • Kwon, Younghwi ; 
  • Kim, Seyeon ; 
  • Jo, Myungjin ; 
  • Jeon, Yu-Mi ; 
  • Cheon, Mookyung ; 
  • Lee, Seongsoo ; 
  • Kim, Sang Ryong ; 
  • Kim, Kiyoung ; 
  • Kim, Hyung-Jun
  • 2020-11
  • Lee, Shinrye. (2020-11). The Role of HDAC6 in TDP-43-Induced Neurotoxicity and UPS Impairment. doi: 10.3389/fcell.2020.581942
  • Frontiers Media S.A.
  • View : 607
  • Download : 155

Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo

Article
Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo
  • Leem, Eunju ; 
  • Kim, Hyung-Jun ; 
  • Choi, Minji ; 
  • Kim, Sehwan ; 
  • Oh, Yong Seok ; 
  • Lee, Kea Joo ; 
  • Choe, Young-Shik ; 
  • Um, Jae-Young ; 
  • Shin, Won-Ho ; 
  • Jeong, Jae Yeong ; 
    • et al
  • 2018-04
  • Leem, Eunju. (2018-04). Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo. doi: 10.1038/s41419-018-0491-3
  • Nature Publishing Group
  • View : 926
  • Download : 247
Article
Upregulation of the ERRγ-VDAC1 axis underlies the molecular pathogenesis of pancreatitis
  • Chanda, Dipanjan ; 
  • Thoudam, Themis ; 
  • Sinam, Ibotombi Singh ; 
  • Lim, Chae Won ; 
  • Kim, Myeongjin ; 
  • Wang, Jiale ; 
  • Lee, Kyeong-Min ; 
  • Ma, Jing ; 
  • Saxena, Romil ; 
  • Choi, Jinhyuk ; 
    • et al
  • 2023-05
  • Chanda, Dipanjan. (2023-05). Upregulation of the ERRγ-VDAC1 axis underlies the molecular pathogenesis of pancreatitis. Proceedings of the National Academy of Sciences of the United States of America, 120(20). doi: 10.1073/pnas.2219644120
  • National Academy of Sciences
  • View : 237
  • Download : 0

Vutiglabridin exerts anti-ageing effects in aged mice through alleviating age-related metabolic dysfunctions

Article
Vutiglabridin exerts anti-ageing effects in aged mice through alleviating age-related metabolic dysfunctions
  • Hyeon, Jooseung ; 
  • Lee, Jihan ; 
  • Kim, Eunju ; 
  • Lee, Hyeong Min ; 
  • Kim, Kwang Pyo ; 
  • Shin, Jaejin ; 
  • Park, Hyung Soon ; 
  • Lee, Yun-Il ; 
  • Nam, Chang-Hoon
  • 2023-10
  • Hyeon, Jooseung. (2023-10). Vutiglabridin exerts anti-ageing effects in aged mice through alleviating age-related metabolic dysfunctions. Experimental Gerontology, 181. doi: 10.1016/j.exger.2023.112269
  • Elsevier Inc.
  • View : 336
  • Download : 81
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