Asymmetric Organic Synthesis and Drug Synthesis Laboratory26
Most of drugs, including Remdesivir® as a potential candidate for COVID-19, have chiral carbon-centers and Thalidomide-scandal had brought the importance of stereoselective synthesis of drugs. In this sense, we pursue the development of practical and efficient asymmetric reactions to apply for the lab-scale or bulk-scale synthesis of chiral drugs. To realize that, we focus on 1) the design and the synthesis of novel chiral catalysts, 2) the development of practical reagents, and 3) the development of novel methodology for C-C, C-O, C-N, or C-B bond formations.
Advisor Professor : Jung, Byunghyuck
Asymmetric Organic Synthesis and Drug Synthesis Laboratory Homepage
Advisor Professor : Jung, Byunghyuck
Asymmetric Organic Synthesis and Drug Synthesis Laboratory Homepage
Subject
- ACCESS 4
- REAGENTS 4
- ACTIVATION 3
- ALCOHOLS 3
- COMPLEXES 3
- HYDROSILYLATION 3
- NATURAL-PRODUCTS 3
- nickel catalysis 3
- OXIDATION 3
- REACTIVITY 3
Co-Author(s)
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Recent Submissions
- Regioselective Transformations of Unsaturated Systems Catalyzed by Low-Valent Nickel: Cycloaddition, Hydrosilylation, and Dicarbofunctionalization
- Synthesis of (Z)-Allylsilanes by Cu-Catalyzed Regioselective Protosilylation of Allenes via a Single-Electron Process
- Regioselective Formal Hydroamidation of Alkynes: Synthesis of α-Substituted Acrylamides
- Recent advances in earth-abundant transition metal-catalyzed dihydrosilylation of terminal alkynes
- Chemo- and Regioselective Nickel-Catalyzed Reductive 1,4-Alkylarylation of 1,3-Enynes through an L2NiAr Intermediate