Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cheon, Mookyung | - |
dc.contributor.author | Kim, Choongrak | - |
dc.contributor.author | Chang, Iksoo | - |
dc.date.available | 2017-07-05T08:46:02Z | - |
dc.date.created | 2017-04-10 | - |
dc.date.issued | 2016-03-15 | - |
dc.identifier.issn | 1367-4803 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/2290 | - |
dc.description.abstract | Motivation: The loci-ordering, based on two-point recombination fractions for a pair of loci, is the most important step in constructing a reliable and fine genetic map. Results: Using the concept from complex graph theory, here we propose a Laplacian ordering approach which uncovers the loci-ordering of multiloci simultaneously. The algebraic property for a Fiedler vector of a Laplacian matrix, constructed from the recombination fraction of the loci-ordering for 26 loci of barley chromosome IV, 846 loci of Arabidopsis thaliana and 1903 loci of Malus domestica, together with the variable threshold uncovers their loci-orders. It offers an alternative yet robust approach for ordering multiloci. Availability and implementation: Source code program with data set is available as supplementary data and also in a software category of the website (http://biophysics.dgist.ac.kr) Contact: or iksoochang@dgist.ac.kr. Supplementary information: Supplementary data are available at Bioinformatics online. © 2015 The Author 2015. Published by Oxford University Press. All rights reserved. | - |
dc.publisher | Oxford University Press | - |
dc.title | Uncovering multiloci-ordering by algebraic property of Laplacian matrix and its Fiedler vector | - |
dc.type | Article | - |
dc.identifier.doi | 10.1093/bioinformatics/btv669 | - |
dc.identifier.scopusid | 2-s2.0-84962178077 | - |
dc.identifier.bibliographicCitation | Bioinformatics, v.32, no.6, pp.801 - 807 | - |
dc.subject.keywordPlus | CONSTRUCTION | - |
dc.subject.keywordPlus | EIGENVALUES | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | GENETIC-LINKAGE MAPS | - |
dc.subject.keywordPlus | GRAPHS | - |
dc.subject.keywordPlus | HUMAN-CHROMOSOMES | - |
dc.subject.keywordPlus | LOCI | - |
dc.subject.keywordPlus | MARKERS | - |
dc.subject.keywordPlus | Networks | - |
dc.subject.keywordPlus | SOFTWARE | - |
dc.citation.endPage | 807 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 801 | - |
dc.citation.title | Bioinformatics | - |
dc.citation.volume | 32 | - |
There are no files associated with this item.