1. Journal Articles23

Showing results 1 to 20 of 23

Development of New IL-1R Antagonists with Improved Anti-inflammatory Efficacy

  • Kang, Mooseok ; 
  • Lee, Ae-Ree ; 
  • Jung, Hyeji ; 
  • Jang, Gyubin ; 
  • Kim, Byeongchan ; 
  • Yoon, Sung-Hyun ; 
  • Yu, Je-Wook ; 
  • Ko, Jaewon ; 
  • Um, Ji Won ; 
  • Chang, Iksoo
  • 2026-01
  • Theranostics, v.16, no.5, pp.2561 - 2575
  • Ivyspring International Publisher
  • View : 157
  • Download : 67

Wavenumber-dependent transmission of subthreshold waves on electrical synapses network model of Caenorhabditis elegans

  • Chang, Iksoo ; 
  • Chung, Taegon ; 
  • Kim, Sangyeol
  • 2025-01
  • Chang, Iksoo. (2025-01). Wavenumber-dependent transmission of subthreshold waves on electrical synapses network model of Caenorhabditis elegans. eLife, 13. doi: 10.7554/eLife.99904
  • eLife Sciences Publications
  • View : 286
  • Download : 101

Resting state of human brain measured by fMRI experiment is governed more dominantly by essential mode as a global signal rather than default mode network

  • Park, Kyeongwon ; 
  • Chang, Iksoo ; 
  • Kim, Sangyeol
  • 2024-11
  • Park, Kyeongwon. (2024-11). Resting state of human brain measured by fMRI experiment is governed more dominantly by essential mode as a global signal rather than default mode network. NeuroImage, 301. doi: 10.1016/j.neuroimage.2024.120884
  • Elsevier
  • View : 340
  • Download : 178

Development of equation of motion deciphering locomotion including omega turns of Caenorhabditis elegans

  • Chung, Taegon ; 
  • Chang, Iksoo ; 
  • Kim, Sangyeol
  • 2024-04
  • eLife, v.12
  • eLife Sciences Publications Ltd
  • View : 421
  • Download : 44
  • Lee, Juhwan ; 
  • Sim, Kyoung Mi ; 
  • Kang, Mooseok ; 
  • Oh, Hyun Ju ; 
  • Choi, Ho Jung ; 
  • Kim, Yeong Eun ; 
  • Pack, Chan-Gi ; 
  • Kim, Kyunggon ; 
  • Kim, Kyung Mo ; 
  • Oh, Seak Hee ; 
  • et al
  • 2024-01
  • Lee, Juhwan. (2024-01). Understanding the molecular mechanism of pathogenic variants of BIR2 domain in XIAP-deficient inflammatory bowel disease. Scientific Reports, 14(1). doi: 10.1038/s41598-023-50932-5
  • Nature Publishing Group
  • View : 407
  • Download : 53
  • Kim, Sangyeol ; 
  • Park, Seongjun ; 
  • Chang, Iksoo
  • 2022-08
  • Kim, Sangyeol. (2022-08). Development of quantitative and continuous measure for severity degree of Alzheimer’s disease evaluated from MRI images of 761 human brains. BMC Bioinformatics, 23(1). doi: 10.1186/s12859-022-04903-8
  • BioMed Central
  • View : 469
  • Download : 0
  • Park, Seong Jun ; 
  • Shin, Y.-K. ; 
  • Yoon, J.-Y. ; 
  • Nam, K.-H. ; 
  • Munashingha, P.R. ; 
  • Park, S. ; 
  • Park, S.-Y. ; 
  • Kim, S. ; 
  • Lee, Juhwan ; 
  • Seo, Min Jae ; 
  • et al
  • 2022-04
  • Park, Seong Jun. (2022-04). Computational design of a thermolabile uracil-DNA glycosylase of Escherichia coli. Biophysical Journal, 121(7), 1276–1288. doi: 10.1016/j.bpj.2022.02.027
  • Biophysical Society
  • View : 680
  • Download : 0
  • Chang, Iksoo ; 
  • Park, Seong Jun ; 
  • Lee, Hye-Jin ; 
  • Kim, Inki ; 
  • Park, Sojung ; 
  • Ahn, Mi Kyoung ; 
  • Lee, Juhwan ; 
  • Kang, Moo Seok ; 
  • Baek, In-jeoung ; 
  • Sung, Young Hoon ; 
  • et al
  • 2021-08
  • Chang, Iksoo. (2021-08). Interpretation of XIAP Variants of Uncertain Significance in Paediatric Patients with Refractory Crohn's Disease. Journal of Crohn's and Colitis, 15(8), 1291–1304. doi: 10.1093/ecco-jcc/jjab013
  • Oxford University Press
  • View : 689
  • Download : 0

Impaired formation of high-order gephyrin oligomers underlies gephyrin dysfunction-associated pathologies

  • Kim, Seungjoon ; 
  • Kang, Mooseok ; 
  • Park, Dongseok ; 
  • Lee, Ae-Ree ; 
  • Betz, Heinrich ; 
  • Ko, Jaewon ; 
  • Chang, Iksoo ; 
  • Um, Ji Won
  • 2021-02
  • Kim, Seungjoon. (2021-02). Impaired formation of high-order gephyrin oligomers underlies gephyrin dysfunction-associated pathologies. doi: 10.1016/j.isci.2021.102037
  • Cell Press
  • View : 982
  • Download : 684
  • Hong, Younghee ; 
  • Chang, Iksoo ; 
  • Kim, Choongrak
  • 2021-06
  • Hong, Younghee. (2021-06). Detection of hubs in complex networks by the Laplacian matrix. Journal of the Korean Statistical Society, 50(2), 431–446. doi: 10.1007/s42952-020-00087-0
  • Springer
  • View : 903
  • Download : 0

Structural and molecular insight into the pH-induced low-permeability of the voltage-gated potassium channel Kv1.2 through dewetting of the water cavity

  • Lee, Juhwan ; 
  • Kang, Mooseok ; 
  • Kim, Sangyeol ; 
  • Chang, Iksoo
  • 2020-04
  • Lee, Juhwan. (2020-04). Structural and molecular insight into the pH-induced low-permeability of the voltage-gated potassium channel Kv1.2 through dewetting of the water cavity. PLoS Computational Biology, 16(4), e1007405. doi: 10.1371/journal.pcbi.1007405
  • Public Library of Science
  • View : 815
  • Download : 131

Atomic insights into the effects of pathological mutants through the disruption of hydrophobic core in the prion protein

  • 2019-12
  • Lee, Ju Hwan. (2019-12). Atomic insights into the effects of pathological mutants through the disruption of hydrophobic core in the prion protein. doi: 10.1038/s41598-019-55661-2
  • Nature Research
  • View : 801
  • Download : 229

Structural insight into conformational change in prion protein by breakage of electrostatic network around H187 due to its protonation

  • Lee, Ju Hwan ; 
  • Chang, Iksoo
  • 2019-12
  • Lee, Ju Hwan. (2019-12). Structural insight into conformational change in prion protein by breakage of electrostatic network around H187 due to its protonation. doi: 10.1038/s41598-019-55808-1
  • Nature Research
  • View : 948
  • Download : 215

Molecular mechanism of K65 acetylation-induced attenuation of Ubc9 and the NDSM interaction

  • Naik, Mandar T ; 
  • Kang, Moo Seok ; 
  • Ho, ChunChen ; 
  • Liao, Pei Hsin ; 
  • Hsieh, Yung-Lin ; 
  • Naik, Nandita M ; 
  • Wang, Szu Huan ; 
  • Chang, Ik Soo ; 
  • Shih, Hsiu Ming ; 
  • Huang, Tai Huang
  • 2017-12
  • Naik, Mandar T. (2017-12). Molecular mechanism of K65 acetylation-induced attenuation of Ubc9 and the NDSM interaction. doi: 10.1038/s41598-017-17465-0
  • Nature Publishing Group
  • View : 984
  • Download : 213
  • Latshaw, David C. ; 
  • Cheon, Mookyung ; 
  • Hall, Carol K.
  • 2014-11-27
  • Latshaw, David C. (2014-11-27). Effects of Macromolecular Crowding on Amyloid Beta (16-22) Aggregation Using Coarse-Grained Simulations. Journal of Physical Chemistry B, 118(47), 13513–13526. doi: 10.1021/jp508970q
  • American Chemical Society
  • View : 1093
  • Download : 0

Polymorphism of fibrillar structures depending on the size of assembled A beta(17-42) peptides

  • Cheon, Mookyung ; 
  • Kang, Mooseok ; 
  • Chang, Iksoo
  • 2016-11
  • Cheon, Mookyung. (2016-11). Polymorphism of fibrillar structures depending on the size of assembled A beta(17-42) peptides. Scientific Reports, 6. doi: 10.1038/srep38196
  • Nature Publishing Group
  • View : 1106
  • Download : 189

The C-Domain of the NAC Transcription Factor ANAC019 Is Necessary for pH-Tuned DNA Binding through a Histidine Switch in the N-Domain

  • Kang, Moo Seok ; 
  • Kim, Sang Yeol ; 
  • Kim, Hyo Jung ; 
  • Shrestha, Pravesh ; 
  • Yun, Ji-Hye ; 
  • Phee, Bong-Kwan ; 
  • Lee, Weontae ; 
  • Nam, Hong Gil ; 
  • Chang, Ik Soo
  • 2018-01
  • Kang, Moo Seok. (2018-01). The C-Domain of the NAC Transcription Factor ANAC019 Is Necessary for pH-Tuned DNA Binding through a Histidine Switch in the N-Domain. doi: 10.1016/j.celrep.2018.01.002
  • Cell Press
  • View : 880
  • Download : 131
  • Jun, Yong-Woo ; 
  • Kim, Sangyeol ; 
  • Kim, Kun-Hyung ; 
  • Lee, Jin-A ; 
  • Lim, Chae-Seok ; 
  • Chang, Iksoo ; 
  • Suh, Byung-Chang ; 
  • Kaang, Bong-Kiun ; 
  • Jang, Deok-Jin
  • 2015-04
  • Lipids, v.50, no.4, pp.427 - 436
  • Springer Nature
  • View : 1179
  • Download : 0
  • Cheon, Mookyung ; 
  • Kim, Choongrak ; 
  • Chang, Iksoo
  • 2016-03-15
  • Cheon, Mookyung. (2016-03-15). Uncovering multiloci-ordering by algebraic property of Laplacian matrix and its Fiedler vector. Bioinformatics, 32(6), 801–807. doi: 10.1093/bioinformatics/btv669
  • Oxford University Press
  • View : 1011
  • Download : 0

Structural Conversion of A beta(17-42) Peptides from Disordered Oligomers to U-Shape Protofilaments via Multiple Kinetic Pathways

  • Cheon, Mookyung ; 
  • Hall, Carol K. ; 
  • Chang, Iksoo
  • 2015-05
  • Cheon, Mookyung. (2015-05). Structural Conversion of A beta(17-42) Peptides from Disordered Oligomers to U-Shape Protofilaments via Multiple Kinetic Pathways. PLoS Computational Biology, 11(5). doi: 10.1371/journal.pcbi.1004258
  • Public Library of Science
  • View : 1118
  • Download : 200
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