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Continuous monitoring of deep-tissue haemodynamics with stretchable ultrasonic phased arrays

Title
Continuous monitoring of deep-tissue haemodynamics with stretchable ultrasonic phased arrays
Authors
Wang, ChongheQi, BaiyanLin, MuyangZhang, ZhuoruiMakihata, MitsutoshiLiu, BoyuZhou, SaiHuang, Yi-hsiHu, HongjieGu, YueChen, YimuLei, YushengLee, TaeyoonChien, ShuJang, Kyung-InKistler, Erik B.Xu, Sheng
DGIST Authors
Wang, Chonghe; Qi, Baiyan; Lin, Muyang; Zhang, Zhuorui; Makihata, Mitsutoshi; Liu, Boyu; Zhou, Sai; Huang, Yi-hsi; Hu, Hongjie; Gu, Yue; Chen, Yimu; Lei, Yusheng; Lee, Taeyoon; Chien, Shu; Jang, Kyung-In; Kistler, Erik B.; Xu, Sheng
Issue Date
2021-07
Citation
Nature Biomedical Engineering, 5(7), 749-758
Type
Article
Keywords
B-MODEDOPPLERATTENUATIONVELOCITIESMORTALITYDIAGNOSISCEREBRAL-BLOOD-FLOWCARDIAC RESYNCHRONIZATION THERAPYORGAN SYSTEM FAILURECAROTID-ARTERY
ISSN
2157-846X
Abstract
Stretchable wearable devices for the continuous monitoring of physiological signals from deep tissues are constrained by the depth of signal penetration and by difficulties in resolving signals from specific tissues. Here, we report the development and testing of a prototype skin-conformal ultrasonic phased array for the monitoring of haemodynamic signals from tissues up to 14 cm beneath the skin. The device allows for active focusing and steering of ultrasound beams over a range of incident angles so as to target regions of interest. In healthy volunteers, we show that the phased array can be used to monitor Doppler spectra from cardiac tissues, record central blood flow waveforms and estimate cerebral blood supply in real time. Stretchable and conformal skin-worn ultrasonic phased arrays may open up opportunities for wearable diagnostics. A prototype skin-conformal ultrasonic phased array enables the monitoring of physiological signals from deep tissues, as shown for the measurements of cardiac Doppler waveforms and central and cerebral blood flows.
URI
http://hdl.handle.net/20.500.11750/15369
https://media.springernature.com/w200/springer-static/cover-hires/journal/41551/5/7
DOI
10.1038/s41551-021-00763-4
Publisher
Nature Publishing Group
Related Researcher
  • Author Jang, Kyung-In Bio-integrated Electronics Lab
  • Research Interests Extreme mechanics; Stand-alone electronics; Heterogeneous materials; Biocompatible interfaces
Files:
There are no files associated with this item.
Collection:
Department of Robotics and Mechatronics EngineeringBio-integrated Electronics Lab1. Journal Articles


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