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Color-sensitive and spectrometer-free plasmonic sensor for biosensing applications

Title
Color-sensitive and spectrometer-free plasmonic sensor for biosensing applications
Authors
Kim, SeungukLee, YoungjinKim, Jae YeonYang, Jae HoonKwon, Hyuk JunHwang, Jae YounMoon, CheilJang, Jae Eun
DGIST Authors
Kwon, Hyuk JunHwang, Jae YounMoon, CheilJang, Jae Eun
Issue Date
2019-02
Citation
Biosensors and Bioelectronics, 126, 743-750
Type
Article
Article Type
Article
Author Keyword
Biosensing; Color-sensitive analysis; Image processing; Nanohole arrays; Plasmonic sensor; Spectrometer-free
Keyword
Color; Computer software; Image analysis; Image processing; Image resolution; Optical data processing; Plasmonics; Plasmons; Refractive index; Spectrometers; Spectrum analysis; Biosensing; Biosensing applications; International Commission; Nanohole arrays; Optical Instrumentation; Optically transparent material; Plasmonic sensors; Sensitive analysis; Color image processing
ISSN
0956-5663
Abstract
A color-sensitive and spectrometer-free sensing method using plasmonic nanohole arrays and the color components, L* a* and b* of the CIELAB defined by the international commission on illumination (CIE) is introduced for the analysis of optically transparent materials in the visible range. Spectral analysis based on plasmonic nanoparticles or nanostructures can be applied to real-time bio-detection, but complex optical instrumentations and low spatial resolution have limited the sensing ability. Therefore, we take an advantage of color image processing instead of spectral analysis which induces the distinctive color information of plasmonic nanohole arrays with different transparent materials. It guarantees high spatial resolution which is essential to bio-detection such as living cells. To establish our sensing platform, the color components, L* a* and b* were extracted from photo images by an image sensor, statistically processed using a JAVA program, and finally utilized as three individual sensing factors. Additionally, our study on a correlation between the spacing of plasmonic sensors and the color sensitivity to the refractive index reveals geometrically optimal conditions of nanohole arrays. The weighted mean calculation with the three individual sensing factors offers an enhanced distinction of the optical difference for transparent materials. In this work, a color sensitivity of 156.94 RIU−1 and a minimum mean absolute error of 1.298×10−4 RIU were achieved. The difference in the refractive index can be recognized up to 10−4 level with the suggested sensing platform and the signal process. This unique color-sensitive sensing method enables a simple, easy-to-control, and highly accurate analysis without complicated measurement systems including a spectrometer. Therefore, our sensing platform can be applied as a very powerful tool to in-situ label-free bio-detection fields. © 2018 Elsevier B.V.
URI
http://hdl.handle.net/20.500.11750/9580
DOI
10.1016/j.bios.2018.11.048
Publisher
Pergamon Press Ltd.
Related Researcher
  • Author Moon, Cheil Moon Lab
  • Research Interests Brain convergent science based on chemical senses; olfaction; 감각신경계 기반 뇌융합과학; 후각 신경계
Files:
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Collection:
Department of Information and Communication EngineeringAdvanced Electronic Devices Research Group(AEDRG)1. Journal Articles
Department of Information and Communication EngineeringMBIS(Multimodal Biomedical Imaging and System) Laboratory1. Journal Articles
Department of Brain and Cognitive SciencesMoon Lab1. Journal Articles


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